ABSTRACT
Objective: To determine the prevalence of ovarian cancer, staging, presenting symptoms, gestational age of diagnoses, screening and diagnostic methods and pregnancy outcomes during pregnancy at Siriraj Hospital over a 13-year period (1998-2010). Methods: Medical records of pregnant women diagnosed with ovarian cancer at Siriraj Hospital from 1998 to 2010 were reviewed. Results: During the 13-year period, 1998-2010, eight cases of pregnant women with ovarian cancer were detected. Six cases of ovarian cancer stage I and 2 cases of ovarian cancer stage II were recorded. All of the patients presented with the symptom of abdominal mass. Two cases presented with abdominal pain. Ultrasonography was performed in all cases to confirm the diagnosis. Two patients with stage II ovarian cancer which was diagnosed in early pregnancy, subsequently had abortions. Five cases from 6 cases of those patients with stage I ovarian cancer underwent caesarean delivery while one case had a normal vaginal delivery. Conclusion: Regarding to this 13-year review, the prevalence of ovarian cancer in pregnancy was low. The management of pregnant patients with ovarian cancer depended on the gestational age and the staging of malignancy.
ABSTRACT
Objective: To create a reference centile chart for transverse cerebellar diameter in Thai fetuses throughout gestation. Methods: A total of 780 pregnant women between 13-40 weeks gestation, who attended at the antenatal clinic at Siriraj Hospital, Mahidol University, Bangkok, were recruited. Each fetus was measured only once for the purpose of this study. The mean and fitted centiles were estimated at each week of gestation using linear regression modeling. Results: A total of 752 fetuses were measured for fetal transverse cerebellar diameter. Linear regression models were fitted to estimate the meant 95% confidence interval for transverse cerebellar diameter at each gestational age. The centile chart of this parameter was also presented. Conclusion: Reference centile chart for fetal transverse cerebellar diameter of Thai fetuses was created.