ABSTRACT
In neuroscientific research the field of neurodegeneration is most active in respect to both medical and associated social issues. Neurodegenration is a broad term used for the progressive loss of structure or function of neurons, including neural death. Neurodegenration can be found in many different levels of neuronal circuitry ranging from molecular to systemic. Many neurodegenerative disorders (NDD) occurs as a result of neurodegenerative process. According to National Institute of Neurological disorders and stroke there are more than 600 neurological disorders. Over last few decades there has been great progress with respect to understanding the triggers of most neurodegenerative diseases. Recent advancements in the basic knowledge of such diseases have led to speculation of new therapeutical approaches, to illustrate one, if we look at NDD as proteinopathy, it can be extrapolated that curing one of the disease could probably contribute to a cure of entire group of diseases related to given proteinopathy. The purpose of this article is to overview the history, epidemiology, etiology, leading pathways and possible treatment of neurodegenerative disorders which would possibly reinvigorate efforts to conduct researches in neuroscientific area for the ultimate benefit of the human community.