ABSTRACT
Cytomegalovirus infection is the first cause of viral congenital infections. We studied the incidence of primary cytomegalovirus infection, searching for the presence of antibodies with an ELISA technique, in 939 pregnant women of a low socioeconomic level, attending a public outpatient clinic and 123 pregnant university students, attending a special outpatient clinic for students. The initially seronegative women were tested again during the second and third trimester of pregnancy to identify primary infections. The presence of cytomegalovirus congenital infection in the newborn of infected mothers was investigated isolating the virus in cell cultures from urine samples. There was a higher prevalence of infection among low socioeconomic status women (95 vs 69.9 per cent). Two women (one student and one coming from a low socioeconomic status) had a primary infection and in the newborn of the student, a congenital cytomegalovirus infection was detected. It is concluded that women's socioeconomic condition is not risk factor for cytomegalovirus primary infection during pregnancy
Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Adult , Cytomegalovirus Infections/epidemiology , Cytomegalovirus/pathogenicity , Enzyme-Linked Immunosorbent Assay , Age Factors , Cytomegalovirus Infections/congenital , Cytomegalovirus Infections/transmission , Antibodies/isolation & purification , Socioeconomic Factors , Fluorescent Antibody TechniqueABSTRACT
Se realizó un estudio comparativo de prevalencia de herpes genital en dos grupos de embarazadas de distinto nivel socioeconómico, a través de la realización de una encuesta epidemiológica, estudio serológico y aislamiento viral. En la población de bajo nivel socioeconómico se detectó antecedentes de herpes genital en el 1,5%de ella. El 96%tenía anticuerpos anti-VHS, y en un 2%se aisló virus herpes simplex en el momento del parto sin detectarse ningún caso de herpes neonatal. En las embarazadas de alto nivel socioeconómico se obtuvo el antecedente de herpes genital en el 4,8%de ellas. Un 87%tenía anticuerpos antiherper y se aisló este virus en el 0,5%de esta población, detectándose un caso de herpes neonatal. Se discuten los factores que generan las diferencias entre las dos poblaciones