ABSTRACT
Osteogenesis imperfecta [OI] as an inherited connective tissue disorder can affect all tissues that contains type I collagen. Well-known cardiac complications of this disease such as aortic root dilatation, aortic regurgitation and mitral valve prolapse have been rarely reported in the literature. Coronary artery aneurysm is a rare cardiac complication in OI, as reported in a 19 year old female presenting with myocardial infarction and hypotension
ABSTRACT
Carbon monoxide [CO] poisoning, though with different sources, is one of the most deadly emergencies in all countries. CO can threaten men's life by several paths especially cardiac complications, which can mimic other cardiac problems such as myocardial infarction. The objective of this study was to determine ECG findings and serum troponin I levels in CO poisoned patients. In this analytical cross-sectional study, 63 CO poisoning patients were consecutively included from hospital's emergency departments. CO content was measured by a CO-oximeter and an electrocardiography was taken first thing on admission. Arterial blood gas [ABG], troponin I and other data was collected afterwards. Data were divided by age groups [adults and children] and gender. CO content was significantly higher only in subjects with normal T wave compared to patients with inverted T wave in their initial ECG [P=0.016]. No other significant difference was noticed. None of the ABG findings correlated significantly with CO content. Also no significant correlation was found with CO content after stratification by gender and age groups, but pH in children [r=-0.484, P=0.026]. CO content was significantly higher in adults [P=0.023], but other ABG data were not significantly different. Only 3 patients had elevated troponin I. Receiver operating characteristic [ROC] analysis showed no significant cutoff points in CO content for ECG changes. No significant specific change in electrocardiograms [ECG] could contribute carboxyhemoglobin content in carbon monoxide poisoned patients. In addition, no specific difference was found between adults and pediatric subjects' ECGs. All other findings seemed to be accidental