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1.
Int. braz. j. urol ; 48(1): 54-66, Jan.-Feb. 2022. tab, graf
Article in English | LILACS | ID: biblio-1356296

ABSTRACT

ABSTRACT Introduction: The therapeutic role of pelvic lymph node dissection (PLND) in prostate cancer (PCa) is unknown due to absence of randomized trials. Objective: to present a critical review on the therapeutic benefits of PLND in high risk localized PCa patients. Materials and Methods: A search of the literature on PLND was performed using PubMed, Cochrane, and Medline database. Articles obtained regarding diagnostic imaging and sentinel lymph node dissection, PLND extension, impact of PLND on survival, PLND in node positive "only" disease and PLND surgical risks were critically reviewed. Results: High-risk PCa commonly develops metastases. In these patients, the possibility of presenting lymph node disease is high. Thus, extended PLND during radical prostatectomy may be recommended in selected patients with localized high-risk PCa for both accurate staging and therapeutic intent. Although recent advances in detecting patients with lymph node involvement (LNI) with novel imaging and sentinel node dissection, extended PLND continues to be the most accurate method to stage lymph node disease, which may be related to the number of nodes removed. However, extended PLND increases surgical time, with potential impact on perioperative complications, hospital length of stay, rehospitalization and healthcare costs. Controversy persists on its therapeutic benefit, particularly in patients with high node burden. Conclusion: The impact of PLND on biochemical recurrence and PCa survival is unclear yet. Selection of patients may benefit from extended PLND but the challenge remains to identify them accurately. Only prospective randomized study would answer the precise role of PLND in high-risk pelvis confined PCa patients.


Subject(s)
Humans , Male , Prostatic Neoplasms/surgery , Lymph Node Excision , Pelvis , Prostatectomy , Prospective Studies , Lymph Nodes/surgery
2.
Int. braz. j. urol ; 46(supl.1): 79-85, July 2020. tab
Article in English | LILACS | ID: biblio-1134298

ABSTRACT

ABSTRACT Introduction: There is little information on how to prioritize testis cancer (TC) patients' care during COVID-19 pandemic in order to relieve its pressure on the health care systems. Objective: To describe the recommendations for diagnosis, treatment and follow-up of patients with TC amidst COVID- 19 pandemic. Material and Methods: Pubmed search and review of the main urological association guidelines on TC. Results: The biology of TC requires immediate care of patients during diagnosis, initial surgical therapy and management of recurrent disease. Active surveillance is the first choice of management and should be offered to all compliant clinical stage I TC patients provided they understand the need to self-isolate. Active surveillance may also help decrease the demand for intensive care unit beds, ventilators, personal protective equipment, and other critical hospital and human resources by minimizing surgeries without compromising patient outcomes. Complications of therapy and symptomatic patients represent medical emergencies and should be treated immediately. Telemedicine may be useful during follow-up periods. Conclusions: Most stages of testis cancer require urgent care; however, all recommendations must be adapted to local health care priorities considering that most of these patients are at low risk of severe COVID-19 infection.


Subject(s)
Humans , Male , Pneumonia, Viral/epidemiology , Testicular Neoplasms/therapy , Coronavirus Infections/epidemiology , Pandemics , Betacoronavirus , SARS-CoV-2 , COVID-19
3.
Rev. argent. cir ; 75(3/4): 61-7, sept.-oct. 1998. ilus, tab
Article in Spanish | LILACS | ID: lil-224738

ABSTRACT

Antecedentes: Las lesiones cervicales invalidantes son más frecuentes en el rugby que en otros deportes de contacto. Objetivo: Analizar incidencia y puestos de riesgo de lesión cervical invalidante en el rugby argentino. Población: Todos los casos informados a la comisión médica de la UAR y/o a la Fundación Rugby Amistad. Método: Confección de registros y seguimiento telefónico. Evaluación estadística de la probabilidad de lesión según puestos con distribución binomial cumulativa para evaluar la incidencia y probabilidad de lesión según los puestos. Resultados: Se documentaron 14 casos desde 1977 hasta 1995 (menos de 1 caso por año). Edad promedio: 19 años. Vértebras mayormente comprometidas: 4ta, 5ta, 6ta. Delanteros lesionados: 11/14, Tres cuartos: 3/14. Puesto más afectado: Hooker, 7/14. Nueve casos ocurrieron durante la formación del scrum. Todos presentaron tetraplegía inicialmente. Conclusiones: La incidencia de lesiones invalidantes de columna cervical es baja. Los delanteros tienen mayor probabilidad de lesión cervical invalidante que los tres cuartos (p = 0,04). El Hooker tiene mayor riesgo de lesión que el resto de los jugadores (p = 0,017), lo que estaría vinculado al "scrum"


Subject(s)
Humans , Male , Adolescent , Adult , Argentina , Football , Spinal Injuries/etiology , Cervical Vertebrae/injuries , Athletic Injuries/complications , Quadriplegia/etiology , Quadriplegia/rehabilitation , Retrospective Studies , Spinal Injuries/complications , Spinal Injuries/rehabilitation
4.
Rev. argent. cir ; 73(3/4): 82-7, sept.-oct. 1997. ilus
Article in Spanish | LILACS | ID: lil-207980

ABSTRACT

La Hemorragia digestiva alta (HDA) en pacientes trasplantados renales constituye un cuadro de gravedad no solo por poner en riesgo la vida del paciente, sino la funcionalidad del injerto. Se han documentado cuatro casos (1,2 por ciento) de HDA en pacientes trasplantados renales con riñon funcionante sobre un total de 340 trasplantes en 328 pacientes desde el advenimiento de la ciclosporina como droga inmunosupresora en el país en enero de 1986 hasta el 11 de abril de 1996. No hubo defunciones ni pérdidas del injerto directamente vinculadas a la HDA. La baja incidencia de HDA estaria relacionada a la profilaxis perioperatoria con bloqueantes H2 y a la rigurosa selección de los receptores. La cirugía profiláctica pre trasplante no está indicada. El tratamiento quirúrgico esta indicado en los casos refractarios a la terapéutica médica. El adecuado tratamiento y profilaxis de cualquier patología causante de una potencial HDA, especialmente la enfermedad ulceropéptica, y la selección de los pacientes receptores aseguran un trasplante renal con muy baja incidencia de complicaciones hemorrágicas esofagogastroduodenales


Subject(s)
Humans , Male , Adult , Middle Aged , Cyclosporine/therapeutic use , Gastrointestinal Hemorrhage/etiology , Kidney Transplantation/adverse effects , Peptic Ulcer Hemorrhage/physiopathology , Cimetidine/adverse effects , Cimetidine/therapeutic use , Cyclosporine/adverse effects , Cytomegalovirus Infections/complications , Cytomegalovirus/pathogenicity , Gastrointestinal Hemorrhage , Gastrointestinal Hemorrhage/mortality , Helicobacter pylori/pathogenicity , Immunosuppression Therapy/adverse effects , Muromonab-CD3/therapeutic use , Ranitidine/adverse effects , Ranitidine/therapeutic use , Retrospective Studies , Peptic Ulcer Hemorrhage/etiology , Peptic Ulcer Hemorrhage/drug therapy , Peptic Ulcer/etiology , Peptic Ulcer/physiopathology
6.
Actas cardiovasc ; 7(2): 119-23, 1996. ilus, tab
Article in Spanish | LILACS | ID: lil-235135

ABSTRACT

Las fístulas entre la arteria aorta y el tubo digestivo y la aorta y las grandes venas son complicaciones poco habituales de los aneurismas de aorta abdominal. Asimismo, los aneurismas micóticos tienen una baja incidencia. Presentamos aquí un paciente de 80 años, portador de aneurisma micótico de la aorta infrarrenal producido por Salmonella tiphi, complicado con fístula aorto-duodenal y aorto-cava simultáneas, que fue tratado exitosamente con resección del aneurisma, duodenorrafia y by pass axilo-bifemoral


Subject(s)
Humans , Male , Aged , Aneurysm, Infected/complications , Aortic Aneurysm, Abdominal/complications , Aneurysm, Infected/surgery , Aortic Aneurysm, Abdominal/surgery , Arterio-Arterial Fistula/surgery , Arterio-Arterial Fistula/etiology , Arteriovenous Fistula/surgery , Arteriovenous Fistula/etiology , Intestinal Fistula/surgery , Intestinal Fistula/etiology , Mycoses/complications
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