[Central nervous system dysgerminoma. A clinicopathological study of 3 cases]

Intracranial germ cell tumors are rarely seen and typically localize in the pineal or suprasellar region. The largest category of germ cell tumors is dysgerminoma. To describe clinicopathological features and immunohistochemical profile of dysgerminomas. We report three cases of central nervous system dysgerminomas. There were two young women and a man who were 6, 11 and 23 year-old. They presented with symptoms of insipidus diabetes [n=3] with association to visual field defects in the third case. Radiological findings showed a supra seller lesion in two cases. Double localization in the pineal and suprasellar regions was seen in the third case. Histologic examination and immunohistochemical study of surgical specimen were consistent with primary central nervous system dysgerminoma

Salivary gland biopsy: experience of La Rabta Hospital's pathology department

The minor salivary gl and s biopsy is a very common diagnostic procedure in oral medicine rather its efficiency has not been statistically proved. Assessment of Rabta pathologic department experience. 297 biopsies have been studied with special attention to the suspected diagnosis before biopsy and the final histologic result. The minor salivary gl and biopsy confirmed the initial diagnosis in 78 cases. Although if the minor salivary gl and biopsy is in most cases not contributively, it is a very simple procedure which gives the diagnosis of Gougerot-Sjogren disease, amylosis and sarcoidosis

[Gastrointestinal stromal tumor: epidemiology and outcome study in 40 cases]

The aim of this study was to analyze epidemiology and outcome of 40 patients with gastrointestinal stromal tumor [GIST] expressed CD117. All epidemiological data [age, sex, location] and survival data were analyzed retrospectively. The tumors occurred in 17 men and 23 women. Stomach was the most common site of localization [47.5%]. Of the 37 patients without Gleevec treatment, 18 benign cases [66.6%] showed long-term survival [2 to 8 years] and 9 malignant cases [33.3%] were diagnosed. 10 cases were still being in followed [< 2 years]. Gastric tumor's survival was better than extragastric tumor's survival without statistically significance [p>0.05]. Our experience confirms that GIST is an aggressive tumor. 33.33% of them are malignant with recurrence or metastatic potential. Additionally, epidemiologic factors [age, sex and location] do not have a predictive value

[Primary hepatic carctnoid tumor: a case report]

Primary hepatic carcinoid tumors are extremely rare, and fewer than 60 cases have been reported in the literature. Long-term follow-up is necessary for establishing the primary nature of liver carcinoids. We report a case arising in a young 20 years-man having Zollinger-Ellison syndrome on presentation. Intensive and careful investigation revealed no other origin of the tumor. Resection is the treatment of choice for primary hopatic carcinoid tumors. Their prognosis seems to be more favorable when compared with other hepatic carcinomas