ABSTRACT
Cutaneous cholesterol embolism is a disease due to the embolism of cholesterol crystals from ulcerated atheromatous plaques to peripheral vessels of the skin. It has been associated with major vessel surgery, angiography, angioplasty, intra-aortic balloon pump placement, anticoagulation, thrombolytic therapy and cardiopulmonary resuscitation. In addition, it may occur spontaneously. In paraffin-fixed sections, the cholesterol crystals are dissolved and leave needle-like clefts within the lumina of arterioles. We report a case of cutaneous cholesterol embolism in a 72-year-old woman who had purplish gangrenous lesions on both her feet after coronary angiography and percutaneous transluminal coronary angioplasty.
Subject(s)
Aged , Female , Humans , Angiography , Angioplasty , Angioplasty, Balloon, Coronary , Arterioles , Cardiopulmonary Resuscitation , Cholesterol , Coronary Angiography , Embolism , Embolism, Cholesterol , Foot , Plaque, Atherosclerotic , Skin , Thrombolytic Therapy , UlcerABSTRACT
Congenital giant melanocytic nevi (CGMN) are lesions of more than 20 cm in diameter, often in the distribution of a garment. Depigmented zones may appear around several types of acquired lesions such as dermal, junctional, and compound nevi, Spitz nevus, blue nevus, and malignant melanoma. The depigmentation may occur within the lesion, around it, or at a distant site. In contrast, congenital nevi rarely develop depigmentation. Vitiligo-like leukoderma distant from the nevus has developed in only three cases with a CGMN. We report two cases of CGMN with vitiligo which is located away from primary CGMN lesion.