ABSTRACT
BACKGROUND: The aim of this study is to define the cardioprotective effects (functional and metabolic) of newly developed DelNido cardioplegic solution (containing plasma solution, mannitol, magnesium and lidocaine). MATERIAL AND METHOD: This study assessed the function of rat hearts after itermittent infusion of DelNido cardioplegia with different preserving methods(Air or Icebox) for 2hours and perfusing the hearts on a Langendorff apparatus. Heart rate, left ventricular developed pressure (LVDP) and coronary flow, were measured at pre-ischemic, post-reperfusion 15min, 30min and 45min. Coronary flow was standardized to dry heart weight. Each weight was weighted to calculate water content. Creatine kinase-MB isoenzyme release was measured and ultrastructural assessment was done with electron microscopes. DelNido group was better than St, Thomas group and Icebox group was better than Room-air group. CONCLUSION: DelNido cardioplegia have better myocardial protective effects than St. Thomas cardioplegia when they were preserved in the Room-air. But we can not tell the difference between Delnido cardiplegia with Air preserving method and St. Thomas cardioplegia with Icebox.
Subject(s)
Animals , Rats , Cardioplegic Solutions , Creatine , Heart , Heart Arrest, Induced , Heart Rate , Magnesium , Mannitol , Plasma , WaterABSTRACT
BACKGROUND: In neonatal respiratory distress syndrome patients, various types of pulmonary air leak contributes to elevate morbity and mortality. Although early surgical interventions can provide better results in several cases, whole clinical outcomes are poor. This study was designed to investigate the clinical aspects of pulmonary air leak in the neonatal respiratory distress syndrome patients and major contributing factors to mortality. MATERIAL AND METHOD: We retrospectively evaluated 48 cases of pulmonary air leak in the neonatal respiratory distress syndrome patients from September 1994 to May 1997. RESULT: There were 15 cases of primary and 33 cases of secondary pulmonary air leakages. The prominent manifestations were pure interstitial emphysema in 19 cases(39.9%) and combined pneumothorax in 19 cases(39.9%). In clinical aspects, normal birth weight was dominant(83.4%), the onset occurred within 24 hours was in 28 cases(58.8%). The pulmonary diseases were meconium aspiration syndrome(25.2%) and hyaline membrane disease(33.2%). The overall hospital mortality was 25.2%, and the majority were hyaline membrane diseases. CONCLUSION: Although the overral mortality rate of these diseases were high, more detailed studies about immediate treatement, perinatal prevention, intensive care to geriatric problems were needed individually to improve outcomes.
Subject(s)
Humans , Infant, Newborn , Birth Weight , Emphysema , Hospital Mortality , Hyalin , Hyaline Membrane Disease , Critical Care , Lung Diseases , Meconium Aspiration Syndrome , Membranes , Mortality , Pneumothorax , Respiratory Distress Syndrome, Newborn , Retrospective StudiesABSTRACT
The management of chronic empyema remains still disturbing. These patients always have chances to exposure septic conditions. We presents 4 patients of chronic empyema with sepsis who underwent E-flap and Myoplasty with extrathoracic skeletal muscles between December 1994 and March 1997. Two patients who had BPF were treated with intercostal muscle flap as co-procedures. Intervals between first E-flap and second Myoplasty ranged from 5 to 10 months. There was no morbidity or mortality. We think these stepwise procedure offers a chance to terminate these debilitating disease.
Subject(s)
Humans , Empyema , Intercostal Muscles , Mortality , Muscle, Skeletal , SepsisABSTRACT
BACKGROUND: In trauma patients, bony thorax are exposured to the trauma in many cases. With simple x-ray, we can not detect all definitive bony abnormalities, especially in less severe cases. Bone scan is very sensitive diagnostic method in such cases. MATERIALS AND METHODS: We experienced 680 cases and results were as follows. RESULTS: 1. Diagnostic sensitivity was 97.4% and false negative rate was 2.6%. 2. In sensitivity study, the time factor (when we perform bone scan) was the most important thing according to trauma pattern. In rib fracture, sensitive test time was after 1 week. In sternal fracture, sensitive test time was after 1 week, too. In costochondral junction fracture and combined cases, it was after 3 days. CONCLUSIONS: We recommend timely using of bone scan as definitive diagnostic method in bony thorax trauma patients.
Subject(s)
Humans , Rib Fractures , Thorax , Time FactorsABSTRACT
No abstract available.