ABSTRACT
No abstract available.
Subject(s)
Humans , Mycosis Fungoides , Spondylitis, Ankylosing , InfliximabABSTRACT
BACKGROUND: With the advancement of socioeconomic and medical sciences, the number of elderly patients with skin diseases significantly increased. Therefore, the epidemiologic survey of dermatologic disease is in need for the elderly population. OBJECTIVE: The purpose of this study was to evaluate the prevalence of dermatologic diseases in elderly patients and to compare the results with the previous reports in malignant and benign skin tumors. METHODS: We retrospectively reviewed the clinical records of 2,678 outpatients older than 65 years of age, who visited the Department of Dermatology from January 2010 to December 2013. We compared the clinical diagnoses and analyzed the distribution of dermatologic diseases and clinical features, including the factors of age and sex. Among them, 575 patients who received biopsy for skin tumors were pathologically analyzed, confirmed, and classified as malignant or benign tumor. RESULTS: The incidence of skin disease in the group of patients older than 65 years of age was 15.6% (2,678). The ratio of men to women was 1 : 1.13 (1,257 : 1,421). The types of skin diseases in the group were as follows: infectious skin disease (26.1%); eczema (23.2%); epidermal and adnexal nevi and tumors (17.5%); drug eruption, erythema, and urticaria (7.0%); pruritus, psychocutaneous disorder, and neurocutaneous dermatoses (6.6%); papulosquamous disease (3.3%); diseases of the skin appendages (3.2%); disorders of pigmentation (2.5%); diseases of the mucous membrane (2.3%); cutaneous vascular diseases (2.2%); and skin tumors (21.5%). The most common malignant tumors were as follows: squamous cell carcinoma (33.9%), basal cell carcinoma (31.2%), Bowen's disease (19.0%), keratoacanthoma (7.2%), malignant melanoma (5.0%), and lymphoma (1.8%). The most common benign tumors were as follows: actinic keratosis (48.0%), seborrheic keratosis (17.2%), epidermal cyst (12.7%), melanocytic nevus (6.2%), hemangioma (3.7%), milia (2.0%), and hypertrophic scar and keloid (2.0%). The incidence of malignant tumors in women was much higher than in men, with a ratio of 1 : 1.96. CONCLUSION: This study provides useful data on the incidence and the characteristics of elderly skin diseases. Compared to the previous studies, the frequency of malignant tumors was relatively higher and variable. We advise physicians to make the appropriate diagnosis and treatment for the early detection of skin tumor, especially the squamous cell carcinoma and basal cell carcinoma, which are caused by long-term exposure to the sun.
Subject(s)
Aged , Female , Humans , Male , Biopsy , Bowen's Disease , Carcinoma, Basal Cell , Carcinoma, Squamous Cell , Cicatrix, Hypertrophic , Dermatology , Diagnosis , Drug Eruptions , Eczema , Epidermal Cyst , Erythema , Hemangioma , Incidence , Keloid , Keratoacanthoma , Keratosis, Actinic , Keratosis, Seborrheic , Lymphoma , Melanoma , Mucous Membrane , Nevus , Nevus, Pigmented , Outpatients , Pigmentation , Prevalence , Pruritus , Retrospective Studies , Skin , Skin Diseases , Skin Diseases, Infectious , Solar System , Urticaria , Vascular DiseasesABSTRACT
BACKGROUND: Keratoacanthoma (KA) can be clinically differentiated with ease from other dermatoses. However, the differential diagnosis of KA can sometimes be difficult, and some cases clinically suggest that the results of skin biopsies of lesions thought to be KA indicate other diseases. OBJECTIVE: The purpose of this study is to examine the diagnostic yield in submitting clinically diagnosed KA that showed solitary symmetric, firm, erythematous, or skin-colored nodules. METHODS: We retrospectively reviewed the clinical records of 54 patients with a clinical diagnosis or differential diagnosis of KA who received biopsies and visited the department of dermatology from January 2004 to December 2013. We compared clinical and histopathologic diagnoses and analyzed the rate of concurrence. In addition, clinical features, including age, sex, location, and duration were investigated. RESULTS: Of the patients, 40.7% were clinically diagnosed with KA, but the results of the histopathology tests indicated other diseases. The mean age of the patients with KA was 72.8 years, and the ratio of men to women was 1 : 0.92. Of the new patients, 0.07% had KA, and most of the lesion sites (84.0%) were caused by sun exposure. Other diseases that are more common in patients with KA are squamous cell carcinoma (55.2%), basal cell carcinoma (20.7%), seborrheic keratosis (6.9%), verruca vulgaris (6.9%), pyogenic granuloma (3.4%), clear cell acanthoma (3.4%), and Bowen's disease (3.4%). CONCLUSION: Skin lesions thought to be KA need more examinations, and skin biopsies of appearances of clinically atypical lesions that cannot completely exclude the possibility of precancerous or malignant lesions are strongly recommended.
Subject(s)
Female , Humans , Male , Acanthoma , Biopsy , Bowen's Disease , Carcinoma, Basal Cell , Carcinoma, Squamous Cell , Dermatology , Diagnosis , Diagnosis, Differential , Granuloma, Pyogenic , Keratoacanthoma , Keratosis, Seborrheic , Retrospective Studies , Skin , Skin Diseases , Solar System , WartsABSTRACT
BACKGROUND: The incidence of scalp tumors has increased, despite medical advances and environmental improvement. However, few studies have reported the clinical and histopathologic features of scalp tumors. OBJECTIVE: The purpose of this study was to evaluate the clinical and histopathologic features of scalp tumors. METHODS: We retrospectively reviewed the clinical and histopathologic features and occurrence rates of scalp diseases in 418 patients whose lesions were biopsied in the department of dermatology between January 2004 and December 2013. RESULTS: The mean age of patients exhibiting scalp tumors was 44.9 years old. The male to female ratio was 1:0.69. The most common benign scalp tumor diagnosed was seborrheic keratosis (22.6%) followed by epidermal inclusion cyst (15.3%), intradermal nevus (8.7%), sebaceous nevus (7.1%), actinic keratosis (5.2%), pyogenic granuloma (3.0%), neurofibroma (2.5%), compound nevus (2.2%), epidermal nevus (1.1%), dermatofibroma (1.1%), and hemangioma (1.1%). The most malignant scalp tumor diagnosed was basal cell carcinoma (34.6%) followed by squamous cell carcinoma (32.7%), metastatic cancer (11.5%), angiosarcoma (7.7%), Bowen's disease (7.7%), lymphoma (3.8%), and apocrine adenocarcinoma (1.9%). CONCLUSION: This study provides data on the incidence of scalp tumors. The results of our study were different from previous studies possibly owing to regional differences between reported patient populations. We advise physicians to appropriately diagnose and treat scalp tumors at the earliest suspicion of malignancy.
Subject(s)
Female , Humans , Male , Adenocarcinoma , Bowen's Disease , Carcinoma, Basal Cell , Carcinoma, Squamous Cell , Dermatology , Granuloma, Pyogenic , Hemangioma , Hemangiosarcoma , Histiocytoma, Benign Fibrous , Incidence , Keratosis, Actinic , Keratosis, Seborrheic , Lymphoma , Neurofibroma , Nevus , Nevus, Intradermal , Retrospective Studies , ScalpABSTRACT
BACKGROUND: Lip skin diseases are common findings in dermatology. However, most dermatologists are not familiar with the clinical features of lip skin diseases due to the special characteristics of the lip. OBJECTIVE: This study aimed to evaluate the clinical and histopathological features of lip skin diseases. METHODS: We retrospectively reviewed 259 patients who underwent biopsy for labial diseases at the Department of Dermatology from January 2002 to December 2011. We compared the clinical and histopathological diagnoses and analyzed the rate of concurrence and labial tumor distribution. In addition, demographic and clinical features, including age, sex, location, and disease duration, were investigated. RESULTS: The mean age of the patients was 56.8 years and the male-to-female ratio was 1:0.77. Lip skin diseases accounted for 4.1% of all new patients during the study period, with the lower lip being the most commonly affected site (88.4%). The most common disease was actinic cheilitis (35.1%), followed by chronic cheilitis (11.6%), mucocele (10.0%), and squamous cell carcinoma (9.7%). The most common type of tumor was actinic cheilitis (54.8%), followed by mucocele (15.7%), squamous cell carcinoma (15.1%), hemangioma (4.2%), pyogenic granuloma (4.2%), keratoacanthoma (1.8%), and basal cell carcinoma (1.2%). Before the patients came to the university hospital, they received medical treatment at various clinics and departments, including dermatology clinics (55.3%), internal medicine (26.2%) and urology departments (10.7%), and general practitioners (9.7%). CONCLUSION: This study provides novel and useful data on the incidence and characteristics of lip skin diseases. Compared to previous studies, the frequency of lip tumors was relatively high and variable in this study. Based on these results, we advise physicians to, if in doubt, initially diagnose and treat for actinic cheilitis and labial tumors (especially squamous cell carcinoma) caused by long term exposure to the sun.