A Case of Nasopharyngeal Glioma Causing Respiratory Distress in Neonate / 대한이비인후과학회지

Nasal gliomas are rare benign congenital midline tumors composed of heterotopic neuroglial tissue with the potential for intracranial extension. They are commomly seen in newborns and children but rarely in adults. Preoperative diagnostic imaging is essential to delineate the exact site and extension of tumor and to plan the appropriate surgical approach. Endoscopic surgery is considered appropriate for the removal of intranasal glioma without intracranial extension. We experienced a case of nasophryngeal glioma in a newborn who had been presented with respiratory distress. The tumor was successfully removed by endoscopic surgery. So we report this rare case with the review of literatures.

The Association between White Blood Cell Counts and Clustered Features of the Metabolic Syndrome

BACKGROUND: Increased WBC counts have been associated with different components of metabolic syndrome (MS), accompanied by clustering of a number of risk factors for CHD. Because most individuals have one or more of the risk factors for CHD or a cluster of MS symptoms, it may not be appropriate to look only at isolated components. Therefore, the aim of the present study was to examine the association of WBC counts with clustered features of MS in Korean adults. METHODS: The subject of this study included 593 adults (males 344, females 249) aged 20 years or older. Among the subjects, we excluded those who did not have records of physical parameters and blood test results and those who did not complete the questionnaire. We also excluded acutely ill patients. Logistic regression analyses were used to evaluate the association between WBC counts and features of the MS, with an adjustment for age, smoking and alcohol consumption. RESULTS: The relative risks for obesity, hypertension, hypercholesterolemia, low HDL cholesterol levels, hypertriglyceridemia, high fasting plasma glucose levels and hyperuricemia compared with WBC counts or =1, > or = 2, > or = 3, > or = 4 features of the MS also increased as WBC counts increased. CONCLUSION: An increased, albeit normal, WBC counts associates with the cluster of MS of the so-called "insulin resistance syndrome" and suggest that an increased WBC counts may be yet another feature of this syndrome.

Small Cell Neuroendocrine Carcinoma of the Nasal Cavity: A Case Report / 대한이비인후과학회지

Small cell neuroendocrine carcinomas of the sinonasal tract are extremely uncommon tumors, and they have been recognized as a highly aggressive neoplasm with poor prognosis. The authors experienced a case of small cell neuroendocrine carcinoma of nasal cavity in a 72-year old male patient. Histopathologic findings showed a high nucleo/cytoplasmic ratio, and the nuclei were round or oval and hyperchromatic. Immunohistochemical study showed small cell neuroendocrine carcinoma. The chest X-ray and CT scan of chest showed no evidence of primary lung lesion. The patient received chemotherapy, but died from cerebral infarction and its complication. We report our case with a brief review of the literatures.