Two Cases of Malignant Schwannoma in Association with Neurofibromatosis

We report two cases of malignant schwannoma of skin in association with non-familial neurofibromatosis. Case 1, a 47 year old man, had a large subcutaneous tumor on the sacral area and case 2, a 62 year old woman, a painful, ulcerating tumor on the posterior aspect of the left arm. Both cases were histopathologically confirmed as malignant schwannomas and immunohistochemical studies showed 5-100 protein in the tumor cells. After surgical excision of the tumors, case 1 was lost to follow up, while case 2 remained without evidence of disease for more than one and half years.

A case of essential mixed cryoglobulinemia / 대한피부과학회지

A 52-year-old woman with esential mixed cryoglobulinemia (type II ), which was confirmed by cryoglobulin elcct,rophoresis and immunofixation elect,rophoresis, had purpuric skin lesions on the legs. The lesions had a tendency of recurrence for the past 2 years, and moderate degrees of arthralgia and myalgia were accompanied in each time. However, the patient had not been suffered from any internal organ distress caused by the disease proress. Histological examinations of a skin lesions revealed a feature of leukocytoclatic vasculitis, and deposits of IgM, IgG and C; were also recognized. A regimen of small doses of prednisolone was effective for the cutaneous lesions in this patient for 4 months follow-up until this writing. It, seems that the patient has had a mild form of the disease among the clinical spectrum of mixed cryoglobulinemia, with a cryocrit value of 2.4% at the time of her initial visit..

Papulosquamous Skin Lesions in Systemic Lupus Erythematosus / 대한피부과학회지

We present 6 patients with systemic lupus erythematosus who had papulosquamous skin lesions. These skin lesions were consistent with the findings of subacute cutaenous lupus erythematosus(SCLE) clinically and histopathologically. The. distribution of the skin lesions were on the face, upper extremities and upper trunk in one group, and the upper and lower extremities in other group of these patients. After confirmation of the skin lesions as a type of SCLE, they were regressed with anti-malarial and/or systemic corticosteroids, within 2 months in all patients. For the better management of the patient with lupus erythematosus, understanding of clinically distinct LE-specific skin lesions, including the papulosquamous cuta-neous manifestation of SCLE, may be necessary.