ABSTRACT
AbstractLivedo reticularis is a spastic-anatomical condition of the small vessels which translates morphologically by a reticular pattern, interspersing cyanosis, pallor and erythema. The same can be congenital or acquired. Among the acquired, we highlight the physiological livedo reticularis and the idiopathic livedo by vasospasm; the latter configures the most common cause. The drug-induced type is less common. The drugs amantadine and norepinephrine are often implicated. Cyanosis is usually reversible if the causative factor is removed, however, with chronicity, the vessels may become permanently dilated and telangiectatic. We report a case of a patient diagnosed with Parkinson's disease with chronic livedo reticularis associated with the use of amantadine and improvement after discontinuation of the drug.
Subject(s)
Aged , Humans , Male , Amantadine/adverse effects , Antiparkinson Agents/adverse effects , Livedo Reticularis/chemically induced , Livedo Reticularis/pathology , Parkinson Disease/drug therapy , Skin/blood supply , Skin/pathologyABSTRACT
O penfigoide bolhoso (PB) é uma dermatose bolhosa autoimune subepidérmica que comumente afeta indivíduos idosos. O desencadeamento da doença por medicamentos é conhecido, entretanto, pouco descrito na literatura, especialmente casos associados ao uso de enalapril. A interrupção do fármaco desencadeante constitui o pilar terapêutico, entretanto medicações podem ser necessárias. Descrevemos um caso de PB em um paciente com 45 anos associado ao uso do enalapril e discutimos sobre a variante de PB induzida por medicamentos.