1.
Indian J Physiol Pharmacol
;
1976 Oct-Dec; 20(4): 239-41
Article
in English
| IMSEAR
| ID: sea-107381
ABSTRACT
Veratrinic response produced by anthracene-9-carboxylic acid in mice has been used as a model for studying effect of variety of drugs which induce muscle relaxation. None of the drugs listed as general depressants, central muscle relaxants, neuromuscular blocking agents and anti-convulsants were effective even at doses causing 100% loss of righting reflex. Local anaesthetics/direct acting muscle relaxants were effective. This simple model employed in conjunction with Straub's tail test can differentiate various categories of muscle relaxants and their mechanism of action.
Subject(s)
Anesthetics, Local/pharmacology , Animals , Anthracenes/antagonists & inhibitors , Carboxylic Acids/antagonists & inhibitors , Drug Evaluation, Preclinical , Mice , Muscle Contraction/drug effects , Muscle Relaxation/drug effects
2.
Article
in English
| IMSEAR
| ID: sea-17390
Subject(s)
Animals , Fibrinogen/analysis , Hot Temperature , Humans , Nephelometry and Turbidimetry/methods , Rats
3.
Indian J Physiol Pharmacol
;
1969 Jul; 13(3): 157-62
Article
in English
| IMSEAR
| ID: sea-108724