Two cases of surgically treated extramammary Paget's disease guided by photodynamic diagnosis / 대한피부과학회지

Extramammary Paget's disease is a rare malignancy occuring mainly in apocrine gland- bearing areas such as vulva, scrotum, perianal area, and axilla. Histopathologically, the Paget's cells are usually confined within the epidermis and may be associated with underlying adenocarcinoma. Although surgical excision is the treatment of choice, the clinical demarcation of the lesion is still a frequent problem in the treatment of extramammary Paget's disease. We tried photodynamic diagnosis to determine the surgical margin of extramammary Paget's disease and with surgical excision guided by photodynamic diagnosis successfully treated two cases.