ABSTRACT
No abstract available.
ABSTRACT
BACKGROUND: Volatile agents have been reported to protect myocardium against ischemia. But, there were a few clinical reports about the myocardial protection of inhalation agents. So we investigated the cardiac protection of sevoflurane in comparison with total intravenous anesthesia (TIVA). The study is a retrospective unrandomized study via the medical record review. METHODS: The records of 102 patients who received off-pump CABG were reviewed. One patient group received TIVA by midazolam and sufentanil continuous infusion (TIVA group, n = 68), and the other patient group received an inhalational anesthesia by sevoflurane (sevoflurane group, n = 34). Except maintenance of anesthesia, two groups of patients received an identical surgical, anesthetical, and postoperative care. At arrival in the intensive care unit, and after 1, 2, 3 and 5 days, serum cardiac enzyme levels were measured. RESULTS: All the median values of cardiac enzyme concentrations were lower in the sevoflurane group than TIVA group. Moreover, there were the significant differences between groups at the immediate postoperative CK-MB (median 4.7 ng/ml versus 5.9 ng/ml (P = 0.049)), 1-5 days postoperative LD (1 day 271.5 U/L versus 292 U/L (P = 0.045), 2 day 227.5 U/L versus 270 U/L (P = 0.009), 3 day 215 U/L versus 250 U/L (P = 0.030), 5 day 218 U/L versus 231 U/L (P = 0.005)), and 1, 3 postoperative troponin I level (0.485 ng/ml versus 1.12 ng/ml [P = 0.029], 0.090 ng/ml versus 0.235 ng/ml [P = 0.047] respectively). CONCLUSIONS: Sevoflurane lowered cardiac enzyme levels in comparison with TIVA after off-pump CABG anesthesia. These data suggest a cardioprotective effect of sevoflurane during CABG.
Subject(s)
Humans , Anesthesia , Anesthesia, Intravenous , Coronary Artery Bypass, Off-Pump , Inhalation , Intensive Care Units , Ischemia , Medical Records , Methyl Ethers , Midazolam , Myocardium , Postoperative Care , Retrospective Studies , Sufentanil , Troponin IABSTRACT
The aims of this study were; 1) to develop the final version of the Korean Roland-Morris Disability Questionnaire (RDQ), and 2) to compare the responsiveness between the RDQ and the Oswestry Disability Index (ODI) scores in patients having low back pain. The psychometric properties of the final Korean RDQ were evaluated in 221 patients. Among them, 30 patients were reliability tested. Validity was evaluated using an 11-point numerical rating scale (NRS) and the Korean ODI. The receiver operating characteristic (ROC) curve analysis of the RDQ and the ODI was compared in 54 patients with lumbar zygapophyseal (facet) joint pain. There was a moderate relationship between the RDQ and NRS (r = 0.59, P < 0.01) and a strongly positive correlation between the RDQ and the ODI (r = 0.76, P < 0.001). The Korean RDQ with the higher area under the ROC curve showed a better overall responsive performance than did the ODI in patients with lumbar facet joint pain after medial branch radiofrequency neurotomy (P < 0.01). The results of the study present the final version of the Korean RDQ is valid for assessing functional status in a Korean population with chronic low back pain.
Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Disability Evaluation , Disabled Persons , Low Back Pain/diagnosis , Pain Measurement , Psychometrics , Surveys and Questionnaires , Republic of Korea , Research Design , Severity of Illness IndexABSTRACT
Epidural analgesia is frequently used for the management of labor pain in parturients. The neurologic complications of epidural analgesia are rare, but they are catastrophic when they occur. We report here on a case of bilateral femoral neuropathy in a vaginal delivery patient with epidural analgesia. The patient complained of weakness of both thighs and numbness around both knees. Neurologic examination and electromyographic study revealed that they occurred due to the delivery itself. The patient had not fully recovered at eight weeks after delivery. The declining incidence of postpartum femoral neuropathy may reflect a reduced duration of labor in accordance with modern obstetric practice, and particularly the more frequent use of Caesarean delivery. The exact etiology of postpartum femoral neuropathy is unknown, and the possible factors are direct compression of nerves that are proximal within the pelvis by either the fetal head or birthing instruments, or this malady is the result of pressure induced ischemia at the level of the inguinal ligament when the pregnant woman is in the lithotomy position.
Subject(s)
Female , Humans , Pregnancy , Analgesia, Epidural , Femoral Neuropathy , Head , Hypesthesia , Incidence , Ischemia , Knee , Labor Pain , Ligaments , Neurologic Examination , Parturition , Pelvis , Postpartum Period , Pregnant Women , ThighABSTRACT
Transfusion-related hyperkalemic cardiac arrest (TRHCA) is a serious complication of administration of packed red blood cell (P-RBC). We present a case of repeated TRHCAs in a 13 month-old girl, who was undergoing intra-abdominal huge mass excision. There were three consecutive TRHCAs during the operation. The first (11.7 mM of K+) and the second (9.5 mM of K+) cardiac arrests were successfully resuscitated. However, the last cardiac arrest (8.9 mM of K+) was failed to be recovered with conventional treatment. Risk factors of TRHCA such as hypocalcemia, hypoxemia, acidosis, hyperglycemia, hyperlactatemia, and low cardiac out state were combined. The transfused P-RBCs were all irradiated. In this situation, processing of P-RBC using an autotransfusion device before the transfusion should be considered to prevent hyperkalemia in addition to conventional treatment of TRHCA.