ABSTRACT
Background: Metabolically obese normal-weight [MONW] children and adolescents are characterized by body mass index [BMI] lower than +1SD with metabolic disorders such as hyperglycemia, hypertriglyceridemia, and/or hypertension. This study wants to determineprevalence of MONW, metabolically benign normal weight [MBNW], metabolically abnormality obese [MAO] and comparethe components of metabolic syndrome [MetS] in some Iranian normal-weight children and adolescents in Ahvaz, Iran
Methods: This cross-sectional study was conducted on 1124 boys and 1128 girls, aged 10-18 y, Ahvaz, Khuzestan.Participants were selected from 6 health centers in Ahvaz by a multistage cluster random sampling method. The Mets was defined according to the modified Adult Treatment Panel III [ATP III]. Anthropometric measurements and blood pressure were measured according to standard protocols. Fasting blood samples were collected for biochemical assessment
Results: MetS prevalence in normal weight group was 5.4% and 1.45% in boys and girls, respectively [P = 0.001] showing a significant difference. Triglyceride abnormality percentages [MBNW = 23.9%, MAO = 88.8%, MONW = 91%] and high density lipoprotein [MBNW = 19.2%, MAO = 73.8% and MONW = 67.2%] were higher than other MetS components in these groups
Conclusions: Since BMI in children and adolescents with metabolically obese-normal weight is normal the continuous measurements and treatment of MetS components especially in boys are important from public health view. The components mean of MetS was higher in MONW and MAO individuals compared with MBNW
ABSTRACT
Objective: The aim of this study was to investigate thyroid function tests in Gestational Diabetes Mellitus [GDM] and pre-gestational DM and control group
Methodology: There were 61 pregnant diabetic women in study group and 35 pregnant women in control group. Serum T4, T3, T3RU, FTI, TSH and Anti TPO Ab were assessed in each person
Results: About 36% of patients had GDM and 64% pre-gestational DM. Thyroid dysfunction was detected in 18% of study group compared with 8.6% of control group [P = 0.2]. There was Thyroid dysfunction in 4.5% of GDM and 25.6% of pregestational DM [P = 0.045]. There was no statistically significant difference between thyroid dysfunction in GDM group and control group [P=0.99].27% of GDM and 36% of pregestational DM and 23% of control group had positive titer of Anti TPO Ab without statistically significant differences among the three groups
Conclusion: Thyroid dysfunction is prevalent in women with pre-gestational DM so, thyroid function should be evaluated in these patients during pregnancy. Rate of thyroid dysfunction in GDM patients is similar to normal pregnant control women. High prevalence of positive titer of TPO Ab was seen in diabetic and nondiabetic pregnant women