ABSTRACT
Introduction: Job stress including physical, social and psychological factors, impact on personnel's health. This problem is more observed in health workers that have continuous communication with patients. Continual and severe stressors are integral part of health worker that exposed at risk of burnout. This study aimed to determine the association between burnout and workplace physical condition in health department staff of Sabzevar University of Medical Sciences.
Methods: This cross - sectional study was conducted among 220 staff of health Department of Sabzevar University of Medical Sciences. Maslach standardized inventory and workplace physical condition questionnaire contain ten question verified by Faculty members of Sabzevar school of health were completed by employee. The collected data were analyzed by spss 16 software.
Results: The highest average of age was in caretaker and administrative staff [41.3 +/- 7.08]. There was a significant relationship between lack of personal accomplishment and depersonalization with workhouse and also significant relationship between lacks of personal accomplishment, depersonalization, and emotional exhaustion whit field of activity was observed. . Physical condition of the workplace was associated with lack of personal accomplishment.
Conclusion: The work environment in healthcare system is always associated with job stresses and its personnel that are susceptible to job burnout. It is proposed by encouraging informal relations within the organization, motivating employee, training, improving of physical conditions of work and meritocracy can implement effective interventions to reduce vulnerability and staff burnout.
ABSTRACT
As an important class of natural products, coumarins exhibit many biological activities and the diversity of their bioactivity is so huge that the pharmacological promiscuity has been applied on their case.Oxypeucedanine also named as prangolarin is a linear furanocoumarin with an oxygenated prenylated substitution at C-5 of the nucleus. To our knowledge, there are few reports on pharmacological and biological activities of this compound. In the present work, we focused on some bioactive aspects of it. In the present work, the compound was purified from Prangos uloptera using TLC and its phytotoxic, antibacterial, antifungal, antioxidant and cytotoxic effects were evaluated by Lettuce assay, disc diffusion method, mycelia radial growth, DPPH and MTT assays, respectively. Our results revealed that oxypeucedanin exhibit considerable phytotoxic activity and might play an allelopathic role for plants. The compound indicated high cytotoxic activity with IC[50] value of 314 micro g/ml. No antipathogenic and antioxidant activity were found for oxypeucedanin in this study. We conclude that oxypeucedanin [found in some vegetables] can be considered as an antiproliferative agent