1.
Cell Journal [Yakhteh]. 2014; 15 (4): 364-371
in English
| IMEMR
| ID: emr-130711
ABSTRACT
Recently, the use of stem cells has expanded into numerous areas including cell therapy. In this study, we investigated the differentiation capacity of human Wharton's jelly stem cells [hWJSCs] into lens fiber cells. Morphological changes and expressions of four crystallin genes [Alpha A, Alpha B, Beta B1 and Beta B3] were studied. The bovine vitreous body has been shown to induce expression of crystallin genes in hWJSCs. By using the vitreous as a lens fiber cell inducer, we showed that Alpha B-, Beta B1- and Beta B3-crystallin genes expressed in hWJSCs