ABSTRACT
Objectives: The aim of this study was to investigate the relationship between Breast Arterial Calcification [BAC] on mammography and the 10-year fatal Cardiovascular Disease [CVD] risk by using SCORE risk system
Methods: The study was conducted from September 2013 to July 2014. A total of 66 women with BAC and 66 age-matched controls without BAC were analyzed. The groups were compared with respect to demographics, clinical, reproductive, laboratory parameters, and 10-year fatal CVD risk
Results: The mean ages of the women in the study was 54.0 years [40-85 years]. Hypertension, systolic blood pressure, levels of serum total cholesterol and the calculated SCORE risk were higher in the BAC [+] group than in the BAC [-] group [p=0.04, p=0.031, p=0.046, and p=0.038 respectively]. Multivariate analysis showed that none of them was independent factor of BAC on mammograms, only the 10-year fatal CVD risk
was close to being statistically significant [OR:1.17, CI:0.98-1.38, p=0.06]
Conclusion: BAC on mammography was found to be related to the 10-year fatal CVD risk as calculated by the SCORE risk score system. Additional large-scale prospective studies are required to further assess whether BAC can be considered a useful screening tool for CVD risk prediction in women who screened for breast cancer by mammography