[Comparison of clinical presentations, wet smear, Papanicolaou smear with Dorset's culture for diagnosis of Trichomonas Vaginalis in doubtful women to Trichomoniasis]

Trichomoniasis is an infection of women urogenital tract that is transferred almost in all cases by sexual contact. This study was done to compare clinical presentations of trichomoniasis and several different paraclinical methods to determine simplest and most efficient method in doubtful patients to trichomonas infection in order to treat infected women and prevent from immethodical use of antibiotics and creation resistant strains. One hundred and fifty fertile women [15-50 years aged] that attended in gynecological clinics and had clinical pictures of trichomoniasis were studied to assess for the presence of trichomonas vaginalis by history, wet mount, papanicolaou smear and dorset's culture. Then data were analyzed. In 150 doubtful patients to trichomoniasis, average of age was 30.56 years. The most common symptoms were frequent pain with sexual intercourse and itching in genital area after persistent, malodor, frothy and yellow vaginal discharge. The most common sign in pelvic examination were frothy, yellowish discharge accompanied by cervical erosion. In 28 patients [18.67%] wet smear, Pap smear and culture were positive simultaneously, papanicolaou smear was positive only in 38 patients. Wet smear is most sensitive and specified for diagnosis of trichomonas vaginalis in doubtful female patients to trichomoniasis, and because of over diagnosing according to clinical manifestation, a confirmatory test should be performed before initiating therapy

[The epidemiological study of cancer in hospitals of Babol Medical University, [1990-2002]]

Cancer is a major medical problem and one of the most causes of death. Considering the young population of Iran and the high rate of malignancies, cancer registry is necessary in order to plan strategies to control and detection of cancer. This study was done on all pathological reports in Shahid Beheshti and Yahyanejad hospitals in Babol during 1990 to 2002. Sex, age and affected organs were determined and the repeated cases were excluded. Then they were categorized in two age groups 15-50 years and over 50 years. Data were analyzed by SPSS and using T-test and [P<0.05] was considered significant. Findings: After removing pediatric cancers, there were 3746 cases. The mean age for all cancer cases was 57.43 +/- 8.99 year, for men was 60.12 +/- 8.89 and for women was 53.42 +/- 9.13 year. Females were more than males in first group and vice-versa in second group that were statistically significant. In both sexes, the most frequency was in 7th decade. There were 2245 cases in males with the three most common cancers being: Stomach [23.69%], esophagus [9.75%] and skin [9.3%] and 1501 cases observed in females with the three most common cancers being: Esophagus [12.99%], breast [12.45%] and stomach [12.25%]. Since gastric cancer in males and esophageal cancer in females were the most frequent malignancies in this study and it seems that there is a relationship between these cancers and dietary, environmental and infective agents, further epidemiological research is needed to establish screening programs, early detection and better treatment

[Evaluation of platelet indices and count in patients with ischemic heart disease compared to normal population]

Atherosclerosis and its complications are a major cause of ischemic heart diseases. Platelets play an important role in initiation of atherosclerosis and coronary thrombus formation. Large platelets are shown to be hemostatically more active. Evaluation of platelet volume parameters could be useful and significant in prediction and differentiation of coronary events. In this study, 100 patients with chest pain were divided into 3 groups according to clinical manifestation and standard diagnostic criteria. 25 patients were with unstable angina, 25 patients with chronic stable angina and 50 patients with non-cardiac chest pain as normal population. Platelet indices and count were assayed within 1 to 3 hours, after sampling from venous blood and collection in K3 EDTA, by a Sysmex KX21 analyzer. Data were provided for each group and surveyed by ANOVA and Tukey tests with Pearson correlation and P-value less than 0.05. Patients with unstable angina had a significant higher MPV [Mean platelet volume] [10.7 +/- 0.23 fl], PDW [Platelet distribution width] and PLCR [Platelet-lerge cell ratio] than those in chronic stable angina and normal group [P<0.05]. MPV in chronic stable angina patients [10.1 +/- 0.2 fl] was higher than normal population [9.5 +/- 0.1 fl] but platelet count and other indices were not statistically significant difference. There were no sex or age differences in MPV amounts in population group. Platelet volume indices are increased in unstable angina probably because of platelet activation and a compensatory volume enhancement. Platelets count reduction in this condition results from platelet consumption. These changes in platelet count and volume could differentiate unstable angina patients from chronic stable patients and normal individuals

[Necrotizing histiocytic lymphadenitis report of two cases [Kikuchi Fujimoto disease]]

Kikuchi Fujimoto disease is a Necrotizing lymphadenitis with benign self-limit process in young women with fever, cervical lymphadenopathy and increased ESR with leukopenia. In this report we introduce two females with Kikuchi Fujimoto disease. The first patient was a 31 years old lady with fever and unilatral cervical lymphadenopathy weight loss from 20 days age. In para-clinical findings ESR=50mm/hr Hb= 10gr/dl. WBC count was 5300/microl bone marrow aspiration and biopsy with lymph node was done. The histopathologic diagnosis was Kikuchi Fujimoto [Necritizing Lymphadenitis]. The second patient was a lady with 35 years old and painful neck mass [behind the sterno-clido mastiod] from 1.5-month age with fever and chill. In paraclinical findings ESR=52 mm/hr WBC 5500/microl, CRP++ lymph node biopsy was done the histopathologic diagnosis was Kikuchi Fujimoto Necrotizing Lymphadenitis. Therefore Kikuchi disease is an important differantial diagnosis in young patients especially women with cervical lympadenopathy and fever [F.U.O]