ABSTRACT
Zinc is an important trace element that has been increasingly implicated in coronary artery disease. The study was designed to compare serum zinc levels in patients of coronary artery disease and healthy controls. It was a prospective, case control study. A total of 125 male participants were divided into healthy controls [n = 25], Ischeamic subjects without myocardial infarction [n = 50], and Ischaemic subjects with previous or present infarction [n = 50] were included in the study. The serum zinc was analysed by atomic absorption spectrophotometery. The mean age in the ischaemic heart disease patients without infarction [Group - A] and with infarction was comparable to the mean age of control group. Family history of ischaemic heart disease and history of smoking were more common among disease groups as compared to controls. Serum zinc levels were found to be significantly low in study sub-group B[2] [83.68 +/- 5.55 micro g/dl] as compared to control group [99.16 +/- 5.18 micro g/dl] and remaining study groups showed insignificant differences. Decreased serum zinc levels are associated with coronary artery disease especially the acute myocardial infarction
ABSTRACT
To compare the frequency of gestational diabetes mellitus in second and third trimester in obese and non-obese women. It was a prospective study conducted at Department of Obstetrics and Gynaecology, Bahawal Victoria Hospital Bahawalpur. Sixty two obese and 62 non-obese women having singleton pregnancy were included in the study at their booking visit at tilde 14-20 weeks of gestation. Women having family history of obesity and chronic ailments and those with age >35 or parity > 5 were excluded. Mean age was 28.12 +/- 2.72 years among the group of obese women as compared to 27.89 +/- 2.34 years in non-obese group. Commonest parity among the obese women was 3-4 [n=31, 50%] compared to 46.8 % [n=29] in non-obese group. Development of gestational diabetes mellitus was 22.58% [n=14] in obese group which was significantly higher than 6.45% [n=4] in non-obese group [p=0.001]. Gestational diabetes mellitus developed in significantly higher number of obese women as compared to non-obese women