Comparison of subcutaneous extralesional and intralesional triamcinolone injection for the treatment of chalazion

To compare the efficacy of injection of extralesional subcutaneous triamcinolone and intralesional triamcinolone in the treatment of primary chalazion. Randomized controlled trial. Armed Forces Institute of Ophthalmology [AFIO] Rawalpindi, from 1[st] September 2011 to 31[st] March 2012. Ninety two patients fulfilling the selection criteria were randomly divided into two groups of 46 patients each group A intralesional triamcinolone [IT] patients received a single extralesional subcutaneous triamcinolone injection while group B extralesional triamcinolone [ET] patients received intralesional triamcinolone injection. Main outcome measure was reduction in chalazion size to 2mm or smaller after steroid injection at 4 weeks follow up visit. The size of chalazion was measured at baseline and then at 2 weeks and 4 weeks post steroid injections. Data analysis was done by "statistical package for social sciences [SPSS] version 13.0 for windows. Both the groups were age matched with mean age of 30.46 +/- 10.09 years in group A and 29.13 +/- 6.04 yrs in group B. Among the subjects, there were 64 male and 28 female patients. Out of 92 patients, resolution was seen in 84.8% [39 out of 46 cases] in ET group and 82.6% [38 out of 46 cases] in IT group at 4 weeks follow up that was not statistically significant [p = 0.45]. Injection of extralesional subcutaneous triamcinolone is as effective as intralesional triamcinolone in treatment of chalazion

Medicinal importance of gems in unani system of medicine. A review

Drugs of mieral origin especially gems, are used I nthe Unani system of Medicine for thousand of years. These gems are used as Muqawwi-e-aam [general body tonic] for the purpose of improving functions of vital organs, increasing Hararat-e-ghareezi [metabolic heat] and Rooh [vital energy or life force] for boosting the immune systems, as blood purifier, and antidote of poisons. These gems are also used in pneumonia, mania, palpiataion, jaundice, grief and depression, anxiety, diseases of brain and heart, weak function of stomach, liver, kidney, illusions, melancholia, tuberculosis epilepsy etc. Emerald, Ruby, Sapphire and Topaz are some of the mineral origin gems which are used in Unani System of Medicine

Randomized placebo controlled clinical trial of unani herbo-mineral cream to evaluate its topical effects on acne vulgaris

A controlled, randomized single blind clinical trial was conducted as per GCP [Good Clinical Practice] Guidelines for the duration of two months on human individuals suffering from Acne vulgaris. The patients were divided into two groups, i e control group treated topically with only cream base and the test group treated topically with the Unani Herbo-Mineral Cream [UHC]. The effects of the UHC were scientifically evaluated in human beings in Acne vulgaris. The assessment of the severity of Acne vulgaris in the control and test groups were made by the "Investigators Global Acne Severity Score". The statistical analysis of the results of severity of Acne vulgaris in the control and test groups was made for the total duration of treatment. Within group comparisons and inter group comparisons were made using ANOVA and paired 't' test respectively. Within group and inter group comparison in the control group shows that the effect of only cream base did not show any significant improvement in the Acne vulgaris of the patients of control group. On the other hand, the within group and inter group comparisons in the test group showed that the differences of the results at each stage of the treatment were very significant The clinical study shows that the test drug 'UHC' has been proved safe and effective in the treatment of Acne vulgaris in the test group in comparison to the control group

Utility of bad [aegle marmelos linn.] in unani medicine

Bael [Aegle marmelos] is an important medicinal plant used in Unani System of medicine, which is cultivated throughout India. It is popularized for having antidiarrhoeal and antidysenteric activity. The present paper is an attempt to summarize the pharmacological actions and medicinal uses of the BaeI plant mentioned in Unani medical literature as well as in currently reported studies