ABSTRACT
The aim of the study was to evaluate the diagnostic performance of fine needle aspiration cytology in the diagnosis of breast lumps. All patients who underwent FNA breast lumps at Rehman Medical Institute, Peshawar during 2006 to 2008 were included in this descriptive crosssectional study. The FNA procedure was performed and interpreted by experienced cyto-pathologists. FNAC of 102 breast lumps were analysed. The age range of the patients was 15-80 years [mean 38.11 years]. Inadequate cases were 2.94%, malignant 30.39%, atypical/suspicious of malignancy 6.86%, and benign 59.80%. Malignant lesions predominated in the 5[th] and 6[th] and benign in the 3[rd] and 4[th] decades of life. FNAC of breast is simple, cost-effective and less traumatic method for diagnosis of breast lumps. Combined with physical examination and imaging studies, it is a highly sensitive diagnostic tool and can reduce the need for open biopsy
ABSTRACT
Adenomyosis is one of the most common, yet under diagnosed, underlying cause of abnormal uterine bleeding. We aimed to evaluate the presence of adenomyosis among the patients who presented with abnormal uterine bleeding. This was a retrospective study carried out on hysterectomy specimens of subjects who presented to the gynaecologist with the complaint of abnormal uterine bleeding not responding to conservative treatment. Excluded are the hysterectomies performed for malignant pelvic neoplasms and hysterectomy following labour for postpartum haemorrhage. A total of 861 women underwent hysterectomy out of which 779 were abdominal and 82 vaginal from Jan 2008 to Dec 2012. Adenomyosis was found in 296 of the 861 specimens studied. The most frequent combination of diagnosis was leiomyoma and adenomyosis. Pathologic conditions associated with adenomyosis were: leiomyomas 150 [50.6%], endometrial polyp 16 [5.4%], genital prolapse 12 [4.05%], chronic endometritis 10 [3.3%], endometrial hyperplasia 5 [1.6%], endocervical polyps 2 [0.6%]. Adenomyosis is a common pathologic finding significantly related to reproductive and menstrual characteristics of the patients
ABSTRACT
To evaluate the diagnostic utility of a haematology analyzer in malaria cases in which the analyzer failed to give a differential leukocyte count. It was an observational study carried out at Pathology Department, Rehman Medical Institute Peshawar, from August 2006 to Jan 2009. During this period a total of 96,865 blood counts were done using Sysmex XT 2000i, haematology analyzer, In 310 consecutive cases, in which the instrument failed to give any differential, 225/310 [73%] were suspected as having blasts or nucleated red cells by the analyzer. In 80/310 [26%] cases in which the instrument did not suspect any blasts or nucleated red cells, some type of malaria was detected on slide examination. Out of the 80 malaria cases, Plasmodium vivax trophozoites were seen in 99% cases with or without ring forms. It included 5% cases of mixed malaria. Using this analyzer, if there is no White Blood Cells differential and no flagging or suspicion, there is a strong possibility of finding trophozoite forms of Plasmodium vivax malaria in peripheral blood