ABSTRACT
Introduction: The fallopian Tube or the oviduct has beennamed after Gabrielis Fallopius, who was the first to describethe tubes very accurately. It is one of the commonest surgicalspecimens received in the histopathological laboratory. It isthe commonest cause of infertility and inflammatory diseases.Malignancy of the fallopian tube is rarely encountered. Thepresent study was undertaken with the following objectivesto evaluate the histological patterns of the fallopian tube insurgically resected specimens and to determine its relationshipwith uterine or ovarian pathology.Material and Methods:A total number of 309 specimensof Fallopian tube were obtained from the patients whounderwent pan hysterectomy with salpingectomy andsalpingo-oophorectomies in Assam Medical College andHospital during the period from October 2016 to September2018. The clinical datas along with gross and microscopicfindings were studied. Incidence and prevalence of variouslesions were calculated.Results: In our study 10cases (3%) had been marked asunremarkable. 77.4% were diagnosed as Chronic Salpingitis,8.95% as Hydrosalpinx and 2.47% as Ectopic Pregnancy. Theother cases comprised mainly of Haematosalpinx andnormalhistologyConclusion: Fallopian tubes can present with differentpathological findings. Malignancies of the Fallopian Tube areuncommon but it has to be examined properly to exclude aprecursor Tubal Pathology
ABSTRACT
Background: Gastrointestinal manifestations of thiamine deficiency have not been well described in literature. Authors aimed to study the symptoms of gastrointestinal beriberi in a cohort of patients of non-alcoholic Wernicke’s encephalopathy and review the relevant literature.Methods: In a retrospective analysis, case records of 52 patients diagnosed with non-alcoholic Wernicke’s encephalopathy were analyzed for the nature of gastrointestinal symptoms, their duration, severity and associated findings, investigations and response to treatment. The available literature on gastrointestinal symptoms in thiamine deficiency disorders and gastrointestinal beriberi was reviewed.Results: Gastrointestinal symptoms were found in 46 of the 52 patients. The most common gastrointestinal symptom in our patients was recurrent vomiting in 42 patients. Eight patients had water brash. Ten patients had epigastric pain and 10 patients had anorexia. Based on the nature and severity of symptoms, patients were evaluated for their symptoms using endoscopy, ultrasonography, amylase and lactate levels, and routine laboratory studies and the results were normal in the majority of patients. Gastrointestinal symptoms settled in all the patients after receiving intravenous thiamine. On reviewing the literature multiple studies were found to have reported prominent gastrointestinal symptoms in patients of Wernickes encephalopathy and other thiamine deficiency related disorders. However, the definition of gastrointestinal beriberi is not clearly stated.Conclusions: Gastrointestinal symptoms were prominent prodromal manifestations in our cohort of Wernicke’s encephalopathy and have also been amply reported in literature. Presence of gastrointestinal symptoms in individuals predisposed to thiamine deficiency without alternative explanation should be enough to label a patient as gastrointestinal beriberi. The study highlights the importance of recognizing gastrointestinal beriberi as a distinct syndrome that may precede the development of Wernicke’s encephalopathy.