Fibroblast Heterogeneity And Its Implications.

After acute inflammation fibroblasts participate transiently in tissue repair by regulating the structure and function of healthy tissues. They also assume an aberrant stimulatory role during chronic inflammatory states including cancer. Heterogeneity of fibroblast applies to functional and phenotypic properties within or across tissues. Fibroblasts are heterogeneous with respect to functional properties, and that certain subpopulations of these cells may be clonally selected and expanded in diseased tissues. These pleiotropic functions highlight the inherent plasticity of fibroblasts and may provide new pathways to understand and therapeutically intervene in diseases. [Monali S NJIRM 2016; 7(5):92-94]

‘CBCT – A positive amelioration in periodontics’.

With the advent in the technology, accurate examination techniques, especially for delicate structures in the oral and maxillofacial regions are required over conventional x-rays, which are mere 2D (2-dimensional) representations of the 3D (3-dimensional) oral structures. Hence, a radiographic tool with a 3D presentation like that of CBCT (Cone beam computed tomography) technology is preferred in pre- and post-treatment assessment of periodontal defects & implant placements.CBCT technology has been used for almost 2 decades, but was previously more expensive to be used in routine dental practice. Recent developments in this field have made its use more practical in routine dentistry.This literature review, emphasizes the invent, development, working, uses, benefits & limitations of dentascan when used in Periodontics.