ABSTRACT
Gossypiboma is a rare yet devastating complication. It may be a sequela to any kind of surgical procedure, however intra-abdominal surgeries are commonly implicated as the cause for this entity. In chronic cases, it may even lead to severe morbidity. We report a case of gossypiboma post vaginal hysterectomy, diagnosed and treated successfully by laparoscopy.
ABSTRACT
Gums and mucilages are preferably used as they are natural materials, for formulating conventional and novel dosage formulations. Natural materials have advantages over synthetic ones since they are chemically inert, nontoxic, less expensive, bio degradable and available in sufficient quantities. The study elaborates isolation of mucilage from the seeds of Cydonia vulgaris Pers. and explores it as tablet disintegrant. The mucilage was evaluated for all the parameters viz. solubility, swelling index, loss on drying, total ash, acid insoluble ash, microbial load and pH as per official monographs. The results confirmed that evaluation parameters were well within the limits. The disintegrating efficiency of isolated mucilage was equivalent to cross-povidone . The prepared batches were evaluated for hardness, friability, % drug content, wetting time, water absorption ratio and in vitro dispersion time. The results of isolated mucilage from Cydonia vulgaris Pers. were very promising.