ABSTRACT
To determine etiology and complications in the patients suffering from cirrhosis of liver in Railway Hospital. Descriptive study. At Medical Unit II, IIMC-T, Pakistan Railway Hospital, Rawalpindi from March 2004 to July 2007. Patients suffering from cirrhosis of liver on the basis of clinical and ultrasonographic findings were included in the study. All other patients of liver disease without evidence of cirrhosis were excluded. Data of the patients regarding the etiological factors and complications of cirrhosis were recorded onaproforma. Out of 141 patients, 56% were males and 44% were females. The mean age was 48.67 years. Most of the patients had HCV infection [61%] followed by HBV infection [20.56%]. Co-infection with HBV and HCV was 3.54%. 3.54% had alcoholic cirrhosis while 5% had post-surgical biliary cirrhosis. Only 2.12% had Wilson's disease and 4.25% were cryptogenic. Most common presentation was simple ascites [33.33%], next was variceal bleeding [27.65%]. Spontaneous bacterial peritonitis was present in 7.8%, hepatic encepha-lopathy in 15.6%, hepatorenal syndrome in 2.12%, generalized bleeding tendency in 3.54% and 5% of cases developed hepatocelluar carcinoma. HCV infection was most common etiology while simple ascites was most common presentation. Emphasis should be on prevention of hepatitis B and C infections through public awareness programmes
ABSTRACT
To find out the seroprevalence of Hepatitis B and C virus among the healthy blood donors at Fauji Foundation Hospital, Rawalpindi. A prospective observational study. From April 2005 to September 2005 at Fauji Foundation Hospital, Rawalpindi. All healthy blood donors reporting to blood bank were screened for Hepatitis B and C. Total number of 1428 donors were screened, among them 97.05% were males. Prevalence of Hepatitis B was 2.45% with a male predominance of 2.38%. Seroprevalence of Hepatitis C was 2.52% with male predominance of 2.52%. Prevalence of Hepatitis B and C is not uncommon in our country. Transfusion of contaminated blood is one of the important cause of its spread. To control its further spread public awareness and health education programs and selection of healthy blood donors should be done