ABSTRACT
Objective: magnesium has a role in glucose homeostasis and insulin sensitivity in ·patients of diabetes mellitus. This study was conducted to compare the levels of serum magnesium in type-2 diabetic patients [controlled and uncontrolled] with non-diabetic controls
Material and Methods: this cross-sectional comparative study was carried out in eighty patients with type-2 diabetes and forty healthy, age and sex matched controls. Diabetic patients were selected after taking detailed history from the outpatient Diabetic Clinic of Services Hospital, Lahore. They were analyzed for serum magnesium, fasting blood glucose and glycosylated hemoglobin [HbA 1 c] levels
Results: mean +/- SD serum magnesium levels of the type 2 diabetic uncontrolled cases were significantly lower [p<0.01] than in the non-diabetic control subjects [0.771 +/- 0.208 mmol/I and 0.901 +/- 0.128 mmol/I]. These levels were non-significantly lower in controlled diabetic patients. There was inverse correlation [r = - 0.084] between the serum magnesium with fasting blood glucose and glycosylated hemoglobin in the type 2 controlled diabetic patients
Conclusion: hypomagnesemia is present in type 2 diabetic patients
ABSTRACT
Background: Diabetic nephropathy is a specific micro vascular disease occurring commonly in diabetes and may sometimes be in very severe form
Material and Method: The aim of this study was to determine the severity of Nephropathy with progressive diabetes. A cross-sectional study of 100 patients attending the diabetic clinic, Mayo Hospital, Lahore was carried out in which blood urea: serum creatinine and albuminuria were evaluated by standard methods
Results: The number of patients having their test values in control range was 34 while the rest 66 patients were grouped according to the severity of nephropathy
Conclusion: The study data analysis leads to the conclusion that nephropathy, prevalent in 66% of study sample, indicated progressive complications with advancement in diabetic history