ABSTRACT
The present study was carried on forty [40] diagnosed ALL [Acute lymphoblastic leukemia], CML [Chronic myeloid leukemia], AML [Acute myeloid leukemia] patients who attended Oncology Centre, Mansoura University. Their ages ranged from 3 to 77 years. They were 27 males and 13 female. Patients were followed up throughout the period of the study. All patients were subjected to the following: Detailed history, clinical examination and Laboratory investigations
Results: CD04 expression was not associated with any of the studied demographic, clinical or laboratory variables. No statistically significant associations were elicited between CD 04 expression and any of the studied prognostic factors of patients. However, a significant positive association was detected between patients who responded to chemotherapy and positive CD04L
Conclusion: CD04L is an independent prognostic factor for relapse free survival, and also an independent prognostic factor for the prediction of good response to chemotherapy, since CD04L positive patients are more liable to achieve complete remission, while CD 04 negative ones are more susceptible to death chemotherapeutic resistance
ABSTRACT
The study was carried out on 50 allergic asthmatic children in rural district in sherbin,dakahlia and received their medication and immunotherapy from clinical immunology unit,zagazig university hospital.fifty patients were divided into 40 patients as active immunotherapy group and 10 patients as control group. Immunotherapy was administered according to preseasonal schedule six month before pollen season.all patients have positive skin prick test and were evaluated clinically and immunologically pre and post immunotherapy [for six month], significant decrease in total serum IgE level P=0.018 [p<0.05] and significant increase in total serum IgG [P<0.001] after immunotherapy in all patients So immunotherapy is considered line of treatment for allergic patients