ABSTRACT
Objectives: to evaluate the role of Diffusion-Weighted Imaging [DWI] in differentiating the various causes of enlarged neck lymph nodes
Design: prospective study
Setting: Department of Radiology Allied Hospital, Faisalabad
Period: from July 2013 to December 2013
Patients and Method: thirty four consecutive patients who presented with clinical suspicion of malignant cervical nodes were included in the study, 19 males [55.9%] and 15 females [44.1%]. Their age ranged from 45 to 70 years, mean age 56.62 +/-7.54 years referred to the radiology department of Allied hospital Faisalabad, complaining of neck swelling, ultrasound showed cervical nodes and all the patients underwent both MRI [T1W, T2W, DWI, ADC] and histopathological examination
Results: according to histopathological analysis we divided the examined patients with lymph nodes [n= 34] into 2 categories: malignant lymph nodes 70.6% [n=24] benign lymph nodes 29.4% [n=10]. DWI and ADC [apparent diffusion coefficient] values revealed 26 malignant lesions [76.5%], 8 benign [23.5%]. The accuracy of the DWMRI was 88.23%. A significant difference between benign and malignant cervical nodes on DWI and on ADC maps is reported. The results obtained were 23 true positive, 3 false positive, 7 true negative and 1 false negative case was identified, yielding a sensitivity of 96%, specificity of 70%, NPV= 87.5% and PPV= 88.5%. The difference between the mean ADC values between benign and malignant lesions was statistically significant [P<0.0001]
Conclusion: diffusion-weighted imaging is a valuable tool in the differentiation of benign and malignant lymph nodes
ABSTRACT
Objective: To evaluate utility of gray scale abdominal ultrasound and liver function tests in the prevalence of Nonalcoholic Fatty Liver Disease in non-working / dependent class of Faisalabad
Study Design: Screening study
Setting: Department of Radiology Allied Hospital, Faisalabad
Duration of Study: 6 months, from December 1 2012 to July 2013
Sample Size: 300. Study Participants -Demographics
Material and Methods: Patients, who denied regular alcohol drinking, were included in the study. A pre-designed study pro forma was filled with relevant parameters i.e. body mass index [BMI], ultrasound, and LFT, s, WHR, lipid profile, clinical assessments were carried out in all cases along with real-time gray scale abdominal ultrasonography as established diagnostic tool. We compared the results of LFT, s and hepatic ultrasound of suspected and non-suspected and are statistically analyzed by SPSS 12
Results: Out of three hundred patients, 200 [67%] female and 100 [33%] were male suspected. Mean age of the patients was 38.93 +/- 8.57 years. The prevalence of fatty liver in males younger than 35 years old was significantly higher [71.7%] where as it markedly increased in females younger than 48 years [65.25%]. Multiple factors analysis reveals that the prevalence of fatty liver was positively correlated to several risk factors, including female, age [>50yr], hyperlipidemia, impaired glucose tolerance/diabetes mellitus, hypertension and overweight/obesity. Fifty one [54%] patients with symptoms like obesiy, fatigue, generalized, weakness, and pain RUQ had fatty liver where as 23.2% had raised Liver enzymes, 20.0% with cholelithiasis and 16.92% with D.M
Conclusions: Routine hepatic ultrasonography and LFT in every suspected patient with symptoms of fatigue, generalized weakness, and pain in RUQ, is able to detect NAFLD as it is cheap and easily available facility in our country
ABSTRACT
Objective: To evaluate ultrasound findings inDengue Haemorrhagic Fever [DHF] and further topredict severity of DHF
Study design: Crosssectional study
Settings: Allied HospitalFaisalabad
Duration of study: 1st July 2011 to 30thNovember 2011
Sample size: 50 Patient
Materialand Methods: Ultrasound was performed on 50patients of ages between 6-59 years with clinicalsuspicion of DHF. Serological tests IgM and IgG onELIZA were performed to confirm the diagnosis,ultrasound was done on 2nd to 08th day all confirmedserologically 50 positive of DHF. These 50 patientdivided into two groups as DHF [Group-I] mild type45 patients and severe type of DHF [Group-II] 05Patient
Result: Group-I patients ultrasoundrevealed gall bladder wall thickening 86.6%,Pericholecystic fluid 44.4%, hepatomegaly 26.6%,splenomegaly 22.2%, ascites17.7%, right pleural effusion 8.8%, left pleuraleffusion nil and pancreatic enlargement 6.6%. InGroup-II ultrasonography revealed gall bladder wallthickening 100%,Pericholecystic fluid 60.0%,hepatomegaly 60.0%, splenomegaly 40.0%, ascites60.0%, right pleural effusion 60.0%, left pleuraleffusion 20.0%, pericardial effusion 20.0%,pancreatic enlargement 40.0% and 60.0% patientwith fulminant hepatic failure
Conclusion: Transabdomino-thoracic sonography can be used asadjunct modality in patients with suspected DHF todetect early signs suggestive of the disease prior toobtaining serologic confirmation test results,especially in a dengue fever epidemic area and alsouseful tool to predict severity of the disease