ABSTRACT
Objective To explore the difference and clinical significance between cerebral infarction and cerebral hemorrhage in patients with acute cerebral infarction.Methods 41 patients with acute cerebral infarction (cerebral infarction group) and 33 patients with acute cerebral hemorrhage (cerebral hemorrhage group) were selected.All patients were detected for plasma TG,TC,LDL,LP (a),G1U,CRP,UA,RBP and HCY,and compared whether they had significant difference,and to draw the ROC curve to the above related biochemical index level,and to judge the diagnostic value of cerebral infarction and cerebral hemorrhage.Results The level of TG,LDL,UA and RBP in cerebral infarction group was significantly higher than that in cerebral hemorrhage group,and the difference was statistically significant (t=2.0～ 4.36,all P＜0.05).The level of GLU and CRP in the cerebral infarction group was significantly lower than that in the cerebral hemorrhage group,and the difference was statistically significant (t=2.99,2.87,all P＜0.05).There was no significant difference in plasma TC,LP(a) and HCY levels between cerebral infarction group and cerebral hemorrhage group (t =0.95～1.85,all P＞0.05).The area under the ROC curve of subjects with TG,LDL,UA,GLU,CRP and RBP level AUC was 0.648,0.652,0.783,0.728,0.749 and 0.649 respectively and there was statistical significance in the judgment of cerebral infarction (all P＜0.05).The area under the ROC curve of plasma UA,GLU and CRP in patients with intracerebral hemorrhage AUC was 0.706,0.804 and 0.837 respectively,and there was statistical significance in the judgment of cerebral hemorrhage.Conclusion There were signifi cant differences between cerebral infarction and cerebral hemorrhage in related biochemical indexes,which could be used to differentiate cerebral infarction from cerebral hemorrhage.