ABSTRACT
<p><b>OBJECTIVE</b>To investigate whether blood stasis is one of the main causes in the pathogenesis of postmenopausal osteoporosis.</p><p><b>METHODS</b>The clinical manifestation of blood stasis syndrome were comprehensively scored in sixty postmenopausal osteoporosis patients, their vascular endothelial function and platelet activating capacity were also detected, and compared with those in 30 healthy women as control.</p><p><b>RESULTS</b>The molecular indexes as vascular endothelial function and platelet activating capacity, as well as comprehensive scores of clinical manifestation of blood stasis syndrome in postmenopausal osteoporosis patients were significantly different to those of healthy women (P < 0.05, P < 0.01).</p><p><b>CONCLUSION</b>There is objective molecular pathologic change of blood stasis syndrome in postmenopausal osteoporosis. Blood stasis plays an important role in pathogenesis of postmenopausal osteoporosis.</p>