ABSTRACT
Objective:To investigate the effect of self-made herbal desensitizer in the treatment of dentine hypersensitivity. Methods:Herbal desensitizer was made of corydalis tuber, asarum herb, long pepper, galangal rhizom and prepared wild aconite root into three different forms:gargle(GG), embrocation(EC) and cataplasm(CP). 750 g/L sodium fluoride paste(SFP) was used as the control. 765 teeth with dentine hypersensitivity in 216 patients were treated with GG,CP,EC and SFP respectively at random. In group CP dental tray was used to carry the desensitizer.The clinical effects were observed in the following 6 months. The effects of the drugs on the obstruction of detinal tubules were observed with scanning electron micoscope(SEM) in the in vitro experiment on 12 extracted teeth.Results:The clinical immediate effective rate(%)of GG,CP,EC and SFP was 57.3(110/192),91.8(179/195),86.9(166/191) and 63.6(119/187) (CP vs GG,EC or SFP P