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1.
Medical Forum Monthly. 2012; 23 (7): 45-47
in English | IMEMR | ID: emr-131841

ABSTRACT

An inverse relationship between the bilirubin level and ischaemic heart disease was accounted. Cross Sectional Study. This study was conducted at Dept. of Biochemistry, Fatima Jinnah Medical College, Lahore from Feb. 2007 to July 2007. Study was performed to determine if serum bilirubin, when combined with various risk factors like lipid and lipoprotein predict ischemic heart disease [IHD]. It is observed that the bilirubin is negatively correlated with hemoglobin, albumin, HDL and LDL-cholesterol. On the other hand a direct correlation with total lipid, cholesterol and ratio of cholesterol/HDL-cholesterol is also observed. High level of serum creatinine level was also found in the patients as compared to normal subject. Our study observed not a definite relationship between serum bilirubin and IHD. Hence the relationships between bilirubin and lipoproteins [risk factors of IHD] require further clarification, although abnormal intermediary metabolism and antioxidant deficiency may be possible linking factors

2.
Medical Forum Monthly. 2012; 23 (7): 48-50
in English | IMEMR | ID: emr-131842

ABSTRACT

We prospectively conducted this study to evaluate the diagnostic value of Pleural fluid estimation and find the rate of tubercular infection in the people with pleural effusion in city of Lahore. Pleural TB is a common form of extrapulmonary disease and may occur in the presence or absence of pulmonary parenchymal disease on the chest radiograph. Prospective Study. This study was conducted in the Biochemistry Department, FJMC, Lahore from May 2010 to Nov. 2010. This study to evaluate the diagnostic value of Pleural fluid estimation and tubercular infection in the people with pleural effusion. All patients aged 22 years and older with clinical and radiographic findings consistent with pleural effusion due to TB admitted to the hospital were evaluated consecutively. The studies were performed on pleural fluid samples: glucose and protein were estimated. Specific gravity was calculated. Cell count, differential cell count, bacterial culture, acid-fast bacilli smear were performed using standard procedures. Specimen was cultured, if effusion contains more than 150 WBC/cumm. It was observed that the level of fluid glucose was increased in both sexes as compared to the normal reported values. Level of fluid protein was more in both sexes as compared to the normal reported values. However level of pH was neutral in both sexes. Present study found that pleural TB is still a major cause of pleural effusion in the city of Lahore, and microbiological and biochemical investigation may be helpful in diagnosing the disease

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