ABSTRACT
Aim: The aim of the present study is to evaluate the status of periodontal disease in the sample population of Jammu region.Materials and Methods: The study included 400 males (200 cigarette smokers and 200 non-smokers) aged 16–65 years.The subjects were randomly selected from the patients attending the dental outpatient Department of Periodontics, IndiraGandhi Government Dental College, Jammu. Community periodontal index (CPI) score was recorded for each patient and aquestionnaire was completed by each patient.Results: Periodontal condition as assessed by CPI score showed that there was a statistically significant difference in thefindings between tobacco consumers and non-tobacco consumers, and periodontal health was altered in the subjects whowere tobacco consumers.Conclusion: The increasing prevalence of periodontal diseases is a concerning problem which needs immediate intervention,if not, it would have a serious negative impact on the future oral health.
ABSTRACT
Aim: The aim of the study was to evaluate the comparative effect of Ornigreat gel and Hexigel as a local drug delivery system in association with scaling and root planing (SRP) in patients with chronic periodontitis. Materials and Methods: A double-blind trial was conducted to test the comparative efficacy of the two commercially available Ornigreat gel and Hexigel at Indira Gandhi Govt. Dental College and Hospital, Jammu. These indices were recorded at baseline (“0 day”), 15th day, 30th day, 60th day, and 90th day in 40 sites, >4 mm pockets in 11 patients among which 20 sites received Ornigreat gel and other 20 sites receive Hexigel following SRP were compared. Results: The results of the study showed that the combination of SRP and Ornigreat gel therapy was more effective in reducing the mean values of gingival index and sulcus bleeding index though not statistically significant, but the values of plaque index showed statistical significance on the 60th day and 90th day, and the probing pocket depths showed statistically significant difference from the 15th day to the 90th day at P < 0.05 in comparison with Hexigel. Conclusion: The Ornigreat gel could be an efficient local drug delivery system when used in adjunct to SRP in comparison with Hexigel.
ABSTRACT
Background: Intestinal permeability increases early in the course of acute pancreatitis and is associated with sepsis and organ failure. Aim: To evaluate the intestinal permeability (IP) and anti-endotoxin antibodies immunoglobulin G and A (AEA IgG and A) in severe acute pancreatitis (SAP) as compared to healthy controls and determine their significance in relation to various complications of SAP. Methods: IP was measured by urinary lactulose/mannitol (LM) excretion ratio and antiendotoxin antibodies by Endocab ELISA kit at days one and seven of admission (D1 and D7). Results: Thirty one patients of SAP [mean age (42.0±15.8) years, APACHE II scores (8.8±5.4) and CT severity index (6.4±2.0)] were included in this study. Infected pancreatic necrosis was detected in 13 (42%) patients of whom three died. Six died of persistent organ failure. Median values of LM ratio at D1 and D7 were similar to those in healthy controls. Patients experiencing complications [organ failure (4/9, 44%), infected pancreatic necrosis (5/10, 50%) and death (1/ 2, 50%)] manifested a substantial increase in their intestinal permeability at D7. Anti-endotoxin antibodies IgG were lower (p=0.003) in patients than the controls at admission. AEA IgG were lower (p=0.03) in non-survivors as compared to survivors at D7. Conclusion: Patients experiencing complications of severe acute pancreatitis showed an increase in intestinal permeability. Higher endotoxemia predicted poor outcome in severe acute pancreatitis.
ABSTRACT
Aluminium phosphide ingestion is a major cause of poisoning-related mortality in tropical countries. Local oesophageal complications due to aluminium phosphide have been reported to occur rarely. We describe 3 patients who survived the intake of aluminium phosphide tablets and developed oesophageal strictures.