ABSTRACT
Secreted phosphoprotein 1 (SPP1) is popularly known as osteopontin (OPN), which plays an important role in initiation and maintenance of pregnancy, as well as in the development of the fetus and milk production. In the present study, investigation of G>T polymorphism in exon 7 region of SPP1 gene was undertaken in 147 Sahiwal and Hariana cattle maintained at Livestock Farm Complex (LFC), DUVASU, Mathura using HpyCH4IV/PCR-RFLP assay. Amplification of SPP1 exon 7 region revealed 204 bp product and HpyCH4IV restriction digestion screening showed monomorphic pattern. Only one type of genotype, namely, TT (204 bp) was observed in population. The frequency of TT genotypes was 100% in all screened samples with T allele (1.0). The results revealed that SPP1 T allele seems to be fixed in screened cattle population. Consequently, we could not perform the association study of this substitution with milk production traits
ABSTRACT
Dental implants are established substitutes for replacing missing teeth. For the successful implant placement, the volume of adequate bone at the recipient site is absolutely essential. Peri-implant dehiscence defects are most often encountered at the site of implant placement that requires bone augmentation. These defects may range from very small lack of marginal bone to large areas of denuded implant surfaces. Recent clinical studies have demonstrated that the application of autogenous bone grafts in conjunction with placement of implants leads to successful coverage of the previously exposed implant surfaces. The present case report highlights the bone augmentation of the peri-implant dehiscence defect by intraoral autogenous bone graft while performing the first-stage implant surgery for multiple edentulous areas.
ABSTRACT
Puberty is the biological transition between the immature and adult reproductive function. This study has been carried out to find out the menstrual pattern, and awareness of the abnormalities in menstrual pattern among school going pubertal age group girls in Dharan. It has been carried out with the aim to follow it with school health education. Cross sectional study was done in 96 girls of two different school of Dharan of the age group ranging from 11 years to 17 years. The median age of menarche was 12 years. There were 6.9% cases of oligomennorhea and 10.0% of hypomenorhea. Menorrhagia was seen in 6.2% of the girls. Spasmodic dysmenorrhea was seen in 67.0% of the girls but the daily activity was hampered only in 20.0%. Out of the 96 students 73.0% were prepared psychologically beforehand. Very less students (8.0%) knew only very little about the abnormalities in menstruation, rest were ignorant about it. Thus, it was seen that these school going girls needed education about the abnormalities of menstruation so that they can differentiate the normal phenomenon from abnormality and report in time in case of aberrance in the menstrual cycle.