ABSTRACT
Background & objectives: The main aim of this research is to provide literature on the Ocimum plant, and to know the significance of the Ocimum species carried out by pharmacognostic study and experimental design for GC-MS. Ocimum genus are very important for their therapeutic potential among the most important aromatic herbs. Methods: Extreme attention has been put on literature reports in which the utilization of tulsi and their pharmacognostic study has been done by performing morphological and microscopic leaf experimental design and by using essential oil through the GC-MS instrumentation method. Results:The utilization of these characteristics would be important for the drug discovery scientist to develop a specific formulation of the crude drug, which will be a magical therapeutic agent in the future, with many advantages. GC-MS chromatogram of Ocimum sanctum, Ocimum canum, and Ocimum gratissimum oil showed major peaks and has been identified after comparison of the mass spectra with the NIST library, indicating the presence of three phytocomponents. From the results, the GC-MS study suggested that anethole which is well reported antimicrobial compound is more in O. canum (2.66%) in comparison to O. sanctum (1,28%) but absent in O. gratissimum. The results indicated that the antimicrobial activity is more in O. canum due to the presence ofa high amount of anethole in comparison to O. gratissimum and O. sanctum. Interpretation & conclusion: The result revealed that O. canum has a microscopic character that can be identified by the characteristic GC MS analysis of extracts to distinguish between different species of the ocimum plant.
ABSTRACT
Traumatic brain injury (TBI) is a one of occurrence with multiple possible neuropsychiatric symptoms, including problems with cognition, emotion, and behavior and deficits in social skills (Hartley 1995). Traumatic brain injury refers to a physiologically significant disruption of brain function resulting from the application of external physical force, including acceleration/deceleration forces (Marr et. al 2002). Severity level of traumatic brain injury can be classified as mild, moderate, and severe. In this context we wanted to study the cognitive functions, social deficits, and state of mood in an individual aftereffect of TBI frequent problems of cognitive, emotional, behavioral, physical, and psychosocial were reported in various studies and substantial source of at least temporary disability and stress to TBI survivors and their families. Hence, we have planned psychological and cognitive management for them. Therefore, in present study, a male of 26 years resident of Jaipur city was studied, the neuropsychological and behavioral functioning was assessed, and findings suggest that impairment in attention and concentration, visual motor functioning, and visuo- spatial functioning, anger, confusion-bewilderment and fatigue state and poor social relationship. Post psychological intervention improvement was observed
ABSTRACT
Pyoderma gangrenosum is a rare, ulcerative, non-infectious neutrophilic dermatosis, commonly associated with underlying systemic disease. The features of pyoderma gangrenosum are not specific histopathologically and for this reason the diagnosis is based on clinical feature. The systemic administration of corticosteroids is the mainstay of treatment. We present five cases of pyoderma gangrenosum of age group ranging from 2 to 75 years. One of these patients was HIV-infected, and one was having discoid lupus erythematosus. The lesions were present on thighs in 3 cases, over back in one and breast in one. Biopsy showed central necrosis with multiple neutrophilic abscesses in epidermis. The dermis showed dense neutrophilic infiltration in both superficial and deep dermis. The lesions responded well to oral corticosteroids except in the case of HIV-infected patient in which minocycline showed considerable improvement.