ABSTRACT
Introduction: Epilepsy is one of the most common disorders of the brain. One of every ten people will have at least one epileptic seizure during a normal lifespan, and a third of these will develop epilepsy. In children the most com-mon forms of convulsion are febrile seizures. Water electrolyte imbalance occurs during acute febrile illness and hy-pocalcaemia is one of them. Hypocalcaemia is also present in cases of seizures. To find out significance of calcium levels in cases of seizures this study was conducted. Aims: To assess the level of ionized calcium in cases of febrile seizure. Methods:This Case –Control study was conducted on fifty cases of febrile seizures and fifty age, weight matched controls and calcium deficiency determined in both groups. The serum ionized calcium levels were estimat-ed by ion selective electrode method using Na, K, Ca analyzer. Results: Mean ionized calcium level was 4.62±0.26mg/dl and 4.88±0.27 mg/dl in study and control groups respectively and this difference was found statistically extremely significant (p<0.001). Conclusion:The findings suggest that a considerable percentage of children having febrile sei-zures are suffering from low level of calcium.
ABSTRACT
Background: Cardiovascular disease (CVD) is consists of a variety of heart disease, illnesses and events that impact the heart & circulatory system, including high blood pressure &coronary artery disease (CAD). Vitamin D is one of the fat soluble vitamins also known as sunshine Vitamin due to its synthesis in the body following exposure to ultraviolet (UV) B rays. The aim of the study is to find the status of Vitamin D & there relation to Acute Coronary Syndrome. Materials and Methods:The present study included 50 cases of diagnosed acute coronary artery disease patients aged between 20 to 60 years and 50 apparently healthy controls and TMT negative matched for age and sex. Serum vitamin D was the measurement by ELISA method.Study Design: ProspectiveObservational Study.Results:The present study showed that significantly decreased levels of serum vitamin D (p<0.001) in acute coronary syndrome patients as compared with healthy controls.Conclusion:Decreased levels of vitamin D are a risk factor for the acute coronary syndrome, and also novel marker of CHD.