ABSTRACT
Objective: In this study our main goal is to assess thesociodemographic characteristics of migraine patients inBangladesh.Methods: This randomized single blind cross over clinical trialwas conducted at Department of Pharmacology, Dhakamedical college, Dhaka from July 2017 to June 2018. Duringthe study, adult 64 migraine sufferers (without aura) attendingin the Out Patient Department of neurology (Headache clinic),Dhaka Medical College Hospital, Dhaka. One half of thesamples were randomly allocated for group A and the otherhalf to group B. Group A: 32 patients will be allocated for theprophylaxis of propranolol. Group B: 32 patients will beallocated for the prophylaxis of flunarizine.Results: During the study, mean age of the group A and groupB was 29.28 and 28.22 years respectively also, group A37.50% were male and 62.50% were female (male: female=1:1.66) and in group B were 34.37% were male and 65.62%were female. After receiving prophylaxis at the end of 1st and2nd phase of trial. Significant improvement was observed ingroup A when they were under trial of propranolol. Similarobservation was also elucidated in group B during 2nd phase oftreatment when drug was crossed over.Conclusion: From our study we can say that, preventivetreatment often makes migraine attacks more responsive toacute migraine therapies, reduces migraine associateddisability, improves the patient’s abilities to function, anddecreases healthcare costs and use of healthcare resource.Further study is needed for better outcome.