ABSTRACT
Objective: Non-pharmacological intervention to manage the health by healthy balanced diet and life style modifications
Study Design: Randomized Cross sectional Study
Place and Duration: Pakistan Council of Scientific and Industrial Research [PCSIR] laboratory Karachi from March 2012 to June 2013
Material and Methods: In this study, 210 volunteers were included [137 male and 73 female] aged between 25-60 years. The study was conducted with the questionnaire being filled at PCSIR labs, Karachi. The study period included from March to May 2012. One year later the same group of volunteers were re-examined from March to June 2013, who managed to alter the diet and life style for one year. The questionnaire was filled by an expert well versed in collecting the data from the patients who attended the OPD at PCSIR labs
Results: The results indicate that a lot of people in our population lead a sedentary life style and do not take part in physical activity which leads to health problems due to comparatively less energy / calories expenditure
Conclusion: Efforts should be made globally to create a public awareness and provide healthy environment to the people about pursuing healthy lifestyles. Several life style behaviors may influence to maintain energy balance over long term. The primary approach for achieving weight loss is lifestyle changes which includes reduced intake of calories and increase in physical activity. Regular, moderate intensity physical activity enhances long term weight maintenance and balance between energy input and output
ABSTRACT
An outbreak of enteric fever occurred in the PCSIR campus colony, Karachi during the months of January-February, 1995 due to contamination of drinking water with sewage water. Forty-four [23.28%] cases out of 189 residents of the colony clinically diagnosed as enteric fever, were followed up. Twenty-eight [63.64%] cases were bacteriologically confirmed as typhoid fever because of the isolation of salmonella typhi from their blood or bone marrow. Culture and sensitivity tests showed that all strains were resistant to amoxycillin, cotrimoxazole, chloramphenicol, augmentin, and fosfomycin but sensitive to quinolones and third generation cephalospoirns. Almost all the adult cases were treated with quinolones for 10-14 days with excellent results. However, children were initially treated with amoxycillin, and then changed over to cefixime and ceftriaxone, due to failure of treatment with amoxycillin. They responded satisfactorily to these drugs. As immediate protective measures. Residents were advised to boil the water before drinking. Chlorination of the water in the underground storage tanks was regularly undertaken. Leakages in the piped supply line were fixed on an emergency basis. These measures helped to avert another typhoid epidemic on the campus