ABSTRACT
Xanthelasma palpebrarum is the most common of the xanthomas with asymptomatic, symmetrical, bilateral, soft, yellow, polygonal papules around the eyelids. Though it is a benign lesion causing no functional disturbance, it is esthetically annoying. The surgical laser offers an extremely elegant and powerful solution to this problem. To evaluate the effectiveness of erbium:YAG and argon lasers in the treatment of xanthelasma lesions. Forty patients were included in the study. Twenty patients [15 patients were bilateral with 30 eyes either in the upper or lower lid and 5 patients were unilateral] were treated with erbium:YAG laser. Another 20 patients [10 patients were bilateral with 20 eyes and 10 patients were unilateral] were treated with argon laser. In the majority of treated patients [either treated with erbium:YAG or argon laser], xanthelasma lesions were completely disappeared or significantly decreased in size. Two patients showed pigmentary changes in the form of hypopigmentation with erbium:YAG laser [one case], another case showed hyperpigmentation. No intraoperative complication was observed. No significant scar or recurrence was observed. Argon laser in xanthelasma is an easy, effective, and safe method of treatment for small lesions and YAG laser is more better for large lesions than argon laser