ABSTRACT
To evaluate the value of using mixed protocol of urinary gonadotrophins for an ICSI/TESE program. Adam International Clinic. Normo-ovulatory women whose partners suffer from severe oligospermia or azospermia were divided into two groups: Group I: Received Fostimon/Merional and Group II received Fostimon/Menogon. All cases underwent ICSI/TESE program and followed-up till clinical pregnancy rate. There was a statistical significant difference in favor of Fostimon/Menogon protocol regarding the number of good quality embryos together with cryo good embryos. More importantly, there was statistically significant difference regarding clinical pregnancy rate in Favor of Fostimon/Menogon protocol. [49/120Vs 33/124]. Mixed protocols were also achieving better results than menogon alone or merional alone. Based on the available results achieved and according to the two cell theory, mixed gonadrotophins using Fostimon/Menogon has become the preferred protocol of ovarian simulation in our ICSI/TESE program