ABSTRACT
<p><b>OBJECTIVE</b>To summarize the experience on diagnosis and treatment of blunt duodenal injuries, and thus to improve the therapeutic skills.</p><p><b>METHODS</b>Clinical data of 34 cases of blunt duodenal injuries admitted to our hospital from 1990 to 2006 were retrospectively analyzed.</p><p><b>RESULTS</b>Among them, 28 cases were cured, 20 cases presented with complications, and 6 cases died. The causes of death were: duodenal or pancreatic fistula in 2 cases, intra-and retroperitoneal infection complicating septicopyemia in 2, disseminated intravascular coagulation in 1 and multiple organ failure in 1.</p><p><b>CONCLUSIONS</b>Misdiagnosis and missed diagnosis predispose to happen for blunt duodenal injuries. Early recognition and surgical intervention are critical to a successful rescue.</p>
Subject(s)
Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Duodenum , Wounds and Injuries , Retrospective Studies , Wounds, Nonpenetrating , Diagnosis , General SurgeryABSTRACT
<p><b>OBJECTIVE</b>To improve the cure rate of patients with abdominal visceral injury complicated by craniocerebral injury.</p><p><b>METHODS</b>Clinical data of 176 cases of abdominal visceral injury complicated by craniocerebral injury were retrospectively analyzed.</p><p><b>RESULTS</b>In this series, 44 cases died and the mortality was 25.0. The main cause of death is abdominal visceral injury combined with shock and severe craniocerebral injury.</p><p><b>CONCLUSIONS</b>It is essential to improve the cure rate by accurate diagnosis at early stage. Abdominal paracentesis and CT should be performed promptly and dynamically. Priority should be given to the treatment of life-threatening injuries.</p>
Subject(s)
Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle Aged , Abdominal Injuries , Diagnosis , Therapeutics , Craniocerebral Trauma , Diagnosis , Therapeutics , Multiple Trauma , Diagnosis , Therapeutics , Viscera , Wounds and InjuriesABSTRACT
Objective To investigate Glypican-3 gene expression and mutation in hepatocellular carcinoma (HCC).Methods Glypican-3 gene expression and mutation in tumor,para-c.ancer and normal tissue of 48 HCCs were detected by RT-PCR and single-strand conformation polymorphism(SSCP),respectively.Results There was no Glypican-3 mRNA expression in para-cancer and normal tissue.Expression rate of Glypican-3 mRNA was 77.1% in tumor tissue,which was correlated with clinical staging and cell differentiation(P