Self-health management ability of college students of Zhuang nationality in underdeveloped areas and assoliated factors / 中国学校卫生

Objective@#To understand the self-health management ability of college students of Zhuang nationality in the economically underdeveloped areas of Guangxi and assoliated factors, and to provide support for improving the health of college students in economically underdeveloped areas.@*Methods@#Five colleges and universities were selected in the economically underdeveloped areas of Guangxi, and 1 042 college students of Zhuang nationality were randomly selected to conduct self-health management ability surveys, and the influencing factors affecting self-health management ability were analyzed.@*Results@#The self-health management ability of Zhuang college students in the economically underdeveloped areas of Guangxi scored (3.63±0.59) points. The scores of boys’ self-health management behaviors were higher than those of girls, which was statistically significant (t=2.92, P<0.01). There was a statistically significant difference in the total scores of cognitive and self-health management among students of different grades (F=8.03, 3.04, P<0.01). The dimensions and total scores of self-health management of medical students were higher than those of other majors, and there was statistical significance (P<0.01). The scores of behavior, environment and total scores of students with different self-assessment status were statistically significant (P<0.01). Regression analysis showed that professional, gender, and self-rated health were the main influencing factors of behavior and environment (P<0.01); gender, grade, and major were the main influencing factors of cognition (P<0.01); grade, professional, self-evaluation health were the main influencing factors of the total score of self-health management (P<0.01).@*Conclusion@#The Zhuang nationality students in the economically underdeveloped areas of Guangxi have higher self-health management ability, but their behaviors are not very good. They should be intervened and guided by different groups to improve the self-health management ability of Zhuang college students.

T cell--associated immunoregulation and antiviral effect of oxymatrine in hydrodynamic injection HBV mouse model

Although oxymatrine (OMT) has been shown to directly inhibit the replication of hepatitis B virus (HBV), limited research has been done with this drug. In the present study, the antiviral effect of OMT was investigated in an immunocompetent mouse model of chronic HBV infection. The infection was achieved by tail vein injection of a large volume of DNA solution. OMT (2.2, 6.7 and 20 mg/kg) was administered by daily intraperitoneal injection for 6 weeks. The efficacy of OMT was evaluated by the levels of HBV DNA, hepatitis B surface antigen (HBsAg), hepatitis B e antigen (HBeAg) and hepatitis B core antigen (HBcAg). The immunoregulatory activity of OMT was evaluated by serum ELISA and flow cytometry. Results shows that OMT at 20 mg/kg inhibited HBV replication, and it was more efficient than entecavir (ETV) in the elimination of serum HBsAg and intrahepatic HBcAg. In addition, OMT accelerated the production of interferon-(IFN-) in a dose-dependent manner in CD4T cells. Our findings demonstrate the beneficial effects of OMT on the enhancement of immunological function and in the control of HBV antigens. The findings suggest this drug to be a good antiviral therapeutic candidate for the treatment of HBV infection.

Intraoperative radiographic technique in defining the safe lateral limits of anterior cervical corpectomy / 中国矫形外科杂志

[Objective]To assess the accuracy and value of radiographic technique using computed tomography(CT) measurements in cadaveric specimens during anterior cervical corpectomy in order to define the safe lateral limit of dissection.[Method]The gutter of C4～6 corpectomy on 5 cadaveric samples was filled with radioopaque dye.An antero-posterior X-ray was used to measure the narrowest distance from dye column to the line of uncovertebral joints.A CT scan confirmed the distance from the borderline of the gutter to vertebral arteries.[Result]The distance between the X-ray dye column and the line of uncovertebral joints averaged 4.7 mm in the left and 4.2 mm in the right.While the distance from the borderline of the gutter to vertebral arteries with CT scan averaged 6.1 mm in the left and 5.9 mm in the right.The measured distance by radiographic technique underestimated the true distance.[Conclusion]Intraoperative radiographic technique can estimate the lateral distance between the gutter of corpectomy and vertebral arteries by measuring the distance from the dye column to the line of uncovertebral joints.This technique provides surgeons an additional margin of safety during anterior cervical corpectomy.

Study on the trend of changes in fetal macrosomia in Yantai during the past 30 years / 中华妇产科杂志

Objective To investigate the changing trend of incidence and the relevant factors in fetal macrosomia. Methods 84 883 newborns during Jan. 1,1970 to Dec. 31,1999 were used to analyze the incidence of fetal macrosomia,the average birth weight,the percentage of superior fetal macrosomia, the distribution of gestational age, the rate of cesarean section and the vaginal delivery, the relevant factors of fetal macrosomia. Results All the cases were divided into 3 groups, one group from 1970 to 1979, the second one from 1980 to 1989, the third one from 1990 to 1999. The incidence of fetal macrosomia for three groups were 2. 6%, 6. 9% and 13 2% ( P