ABSTRACT
The clinical or experimental study proves that Chinese medicine such as Tripteryglum wilfordii, Lignum Sappan, Caulis Sinomenii, Radix Trichosanthis and Herba Artemisiae Annuae have good immunosuppressive activity. Further researches on the immunosuppressive active components from Chinese medicine have been the main direction in recent years. The recent researches on immunosuppressive effect and possible mechanisms for the monomers such as triperine, triptolide, bazilein, potosappanin A, sinomenine, trichosanthin and artemisinin extracted from those Chinese medicine are introduced in this review.
Subject(s)
Animals , Humans , Artemisinins , Pharmacology , Therapeutic Uses , Diterpenes , Pharmacology , Therapeutic Uses , Drugs, Chinese Herbal , Pharmacology , Therapeutic Uses , Epoxy Compounds , Pharmacology , Therapeutic Uses , Immunosuppressive Agents , Pharmacology , Therapeutic Uses , Morphinans , Pharmacology , Therapeutic Uses , Phenanthrenes , Pharmacology , Therapeutic Uses , Plants, Medicinal , Chemistry , Trichosanthin , Pharmacology , Therapeutic UsesABSTRACT
Objective To investigate the distribution of camptothecin(CPT),tryptophan synthase(TSB),and tryptophan decarboxylase(TDC) in Camptotheca acuminata seedlings.Methods The CPT content,TSB and TDC activities in different organs of C.acuminata seedlings subjected to different nitrogen forms treatments by sand culture in greenhouse were determined by HPLC.Results The CPT content in the young leaves of C.acuminata seedlings with different N-forms was significantly higher than that in other organs(P