ABSTRACT
The frequency of chromosomal aberrations in Iran is not definitely known. This study determined the frequency of chromosomal aberrations in a series of couples with two or more spontaneous abortions and compared the findings with that reported from other countries. This was a descriptive study conducted on 100 couples with recurrent abortions. Both partners were karyotyped as part of the primary investigation. Other probable causes of abortion were also investigated. Chromosomal aberrations were found in 8 [8%] of the females and 5 [5%] of the males. The prevalence of chromosomal abnormalities was as follows: 4 [30.8%] balanced reciprocal translocations, 3 [23%] Robertsonian translocations, 3 [23%] pericentric inversions, 1 [7.7%] paracentric inversion, 1 [7.7%] chromosomal marker, and 1 [7.7%] polymorphism 9qh+. The pattern of chromosomal aberrations was similar to that reported in other studies, but the prevalence of chromosomal aberrations was higher