ABSTRACT
@#Objective To investigate the uterine septum clinical treatment effects by hysteroscopy different ways of excision.Methods The treatment effects of 90 uterine septum cases were analyzed retrospectively.Those patients were divided into two groups,One group 45 cases accepted hysteroscopy electrosurgical excision,Another group 45 cases was implemented uterine septum cut off with hysteroscopic miniature scissors.Their operative time,blood loss were recorded and compared,and their mediastinal residual and intrauterine adhesions were retreated again in second hysteroscopy checking after 3 months of the first opration.Results All cases were finish the operation sccssefly without complication happens.The total average surgical time was(20.3±6.8)minutes,the average bleeding volume was(11.2±3.1)ml,and the hospital stay was 1 to 5 days,average of 3.5 days.There was no significant difference between the electric resection and cold knife groups in operation time,intraoperative bleeding,mediastinal residual,uterine cavity adhesion,pregnancy rate and abortion rate(P>0.05).There was no significant difference between the two groups in the sequential treatment of intrauterine adhesions and pregnancy rates with simple estrogen and progesterone(P>0.05),the difference of abortion rate was statistically significant(P<0.05).There was no significant difference between the two groups in the sequential treatment of intrauterine adhesion,pregnancy rate and abortion rate with the combination of intrauterine cross-linked sodium hyaluronate gel and oral estrogen and progesterone(P>0.05).Conclusion There was no clear correlation at intrauterine adhesions,mediastinal remnants in resection methods.The sequential treatment of intrauterine cross-linked sodium hyaluronate gel plus oral estrogen and progesterone after operation is conducive to reducing the adhesion rate and improving the pregnancy rate.
ABSTRACT
Objective To observe effects of Kangshuai Yizhi Capsule on ATP in brain tissue and IL-6, TNF-α in serum of aging model rats, and explore the protective effects of the capsule on brain tissue.Methods Totally 72 rats were randomly divided into a normal group and a model group. The subacutely aging model rats were made by injectingD-gal, then aging rats were numbered and grouped by random number table into the model group, Kangshuai Yizhi high-dose group, Kangshuai Yizhi Capsule low-dose group and Naofukang group. All dose groups were received gavage by giving corresponding doses, while normal group and model group were given the same amount of saline everyday. After treated for 60 days, the activity of Na+-K+-ATP and Ca2+-Mg2+-ATP in brain tissue, and IL-6, TNF-α in serum were detected.Results Compared with normal group, Na+-K+-ATP and Ca2+-Mg2+-ATP were less active (P<0.05), but levels of IL-6 and TNF-α in model group were significantly higher, with statistical significance (P<0.05). Compared with model group, after treated with Kangshuai Yizhi Capsule, Na+-K+-ATP and Ca2+-Mg2+-ATP were more active, and IL-6 and TNF-α levels were down-regulated significantly in dose groups, with statistical significance (P<0.05). Meanwhile, Kangshuai Yizhi Capsule high-dose group showed the most obvious effect among dose groups.ConclusionKangshuai Yizhi Capsule has effects of enhancing activity of ATP in brain tissue and reducing level of proinflammatory factors.