ABSTRACT
Background: Diabetes mellitus is one of the most common chronic metabolic disorders. Nowadays there is an uprising trend toward new approaches in type 2 diabetes management. In this study the effect of Ginger supplementation on blood pressure in type 2 diabetic patients was examined
Methods: 81 patients with type 2 diabetes who were referred to Yazd Diabetes Research Center participated in this randomized clinical trial. Patients were randomly divided into two groups; Placebo [PG] and ginger supplemented [GG] groups. GG were supplemented with 3 ginger capsules [1 g ginger powder in each capsule] and PG received placebo. Systolic blood pressure [SBP], diastolic blood pressure [DBP], Pulse pressure [PP] and mean arterial pressure [MAP] were measured before the intervention, 2[nd] week, 4[th] week, 6[th] week, and at the end of the study [8[th] week]
Results: The SBP, DBP, PP and MAP were decreased significantly in the GG [P = 0.001] group at the end of week 8 and significantly decreased at the end of the study compared to the beginning of the study. No significant changes were observed in the PG. However, its mean was statistically different between two groups at the end of intervention
Conclusion: This study indicated that daily consumption of 3 g of ginger powder in capsules for 8 weeks by patients with type 2 diabetes decreases SBP, DBP, PP and MAP
ABSTRACT
Background: Preliminary clinical trials showed that ginger improved lipid profile in type 2 diabetes patients [T2D]. This trial was carried out to determine the effect of ginger on blood lipid and lipoproteins in T2D
Methods: this is a randomized, double-blind, placebo-controlled trial on 88 T2D conducted in. The patients were randomly divided into two groups of ginger [GG] and placebo [PG], the GG consumed daily 3 one-gram capsules containing ginger powder whereas the other group received capsules of the same color and number as GG but containing cellulose microcrystalline, both after taking meals and for eight weeks. Serum total cholesterol [TC], triglycerides [TG], HDL-c, LDL-c, Apo B100 and Apo A1 were measured at the baseline and the end of trial
Results: Out of 88 patients who participated in the trial, 81 of them accomplished it. No significant changes were observed in mean of TC, TG, HDL-c, and Apo B100 within and between the groups. Serum LDL-c and LDL-c/HDL-c ratio were decreased significantly in the GG [P = 0.03, P = 0.028] at the end of trail but they were not significantly different between the two groups. Serum Apo A1 was increased significantly in the GG [P < 0.05] and PG [P < 0.05] at the end of trial but it was not significantly different between the two groups
Conclusions: This study indicated that daily consumption of 3 g of ginger powder in capsules for 8 weeks by T2D leads to lowering of LDL-c, LDL-c/HDL-c ratio, and Apo A1. Therefore, consumption of this supplementation is appropriate for this patients