ABSTRACT
The chemical constituents of gorgonian Junceella fragilis Ridley, collected from Ximao Island, the South China Sea, were investigated. A new briarane-type diterpenoid, named fragilide Y (1), together with five known compounds (2–6), namely fragilide D (2), cholesterol (3), ergosterol peroxide (4), 2'-deoxythymidine (5) and cis-thyminenol (6), were isolated from the acetone extract of J. fragilis. The structure of the new compound 1 was elucidated by extensive spectroscopic analysis, while the known compounds were identified by comparison with the reported data. In bioassay, none of these compounds displayed obvious anti-inflammatory and cytotoxic effects.
ABSTRACT
OBJECTIVE: To study the chemical constituents of the aerial parts of Emilia sonchifolia. METHODS: The chemical constituents were isolated and purified by chromatographies on silica gel, MCI gel, ODS, and Sephadex LH - 20 columns, as well as RP-HPLC. And their structures were identified on the basis of physicochemical properties and spectral data. RESULTS: Eighteen compounds were obtained from the aerial parts of E. sonchifolia and identified as isorhamnetin-3-O-α-L-rhamnopyranoside(1), afzelin (2), quercetin-7-O-α-L-rhamnopyranoside(3), 5, 2', 6'-trihydroxy-7-methoxyflavone 2'-O-β-D-glucopyranoside(4), quercetin-3-O- α-L-rhamnopyranoside(5), diosmin(6), isorhamnetin-3-O-rutinoside(7), linarin(8), vitexin(9), quercetin-7-O-β-D-glucopyranoside(10), vicenin-2(11), methyl 4-hydroxybenzeneacetate(12), 3, 4-dihydroxybenzeneacetic acid(13), brevifolin(14), chlorogenic acid(15), methyl chlorogenate(16), pedatisectine E(17), and uridine(18), respectively. CONCLUSION: All compounds are isolated from this genus for the first time except compounds 5 and 11.
ABSTRACT
<p><b>OBJECTIVE</b>To study the chemical constituents contained in ethanol extracts from aerial parts of Emilia sonchifolia.</p><p><b>METHOD</b>The compounds were separated and purified with various chromatographic techniques, and their structures were identified on the basis of physicochemical properties and spectral data.</p><p><b>RESULT</b>Fifteen compounds were separated from ethyl acetate fraction of 90% ethanolic extract and identified as rhamnetin (1), isorhamnetin (2), quercetin (3), luteolin (4), tricin-7-O-beta-D-glucopyranoside (5), 8-(2"-pyrrolidinone-5"-yl) -quercetin (6), 5, -2', 6'-trihydroxy-7, 8-dimethoxyflavone-2'-O-beta-D-glucopyranoside (7), succinic acid (8), fumaric acid (9), p-hydroxybenzoic acid (10), 4-hydroxy isophthalic acid (11), 3, 4-dihydroxycinnamic acid (12), esculetin (13), isowedelolactone (14) and uracil (15), respectively.</p><p><b>CONCLUSION</b>All compounds except compound 3 were separated from this genus for the first time.</p>