A nested case control study for risk factors impacting hepatitis B vaccination in Hebei, China / 中华实验和临床病毒学杂志

<p><b>OBJECTIVE</b>Study the risk factors that impact the effectiveness of mass hepatitis B vaccination, and try to amend them in the future.</p><p><b>METHOD</b>Based on the national surveillance of hepatitis B, all the 1734 of 1-15 years old children from Hebei Province were enrolled in the present study and they were divided into case and control group according to their sera HBsAg were positive or not.</p><p><b>RESULTS</b>Mother sera HBsAg positive and the hospital the children were born and earlier year of birth were risk factors.</p><p><b>CONCLUSION</b>The effectiveness of mass neonate hepatitis B vaccination has greatly improved and the future focus should be on finding pregnant HBsAg positive women, and encourage them to give birth in better hospitals, and at the mean time, try to make the neonate hepatitis B vaccination perfect, especially in country areas.</p>

An effective method to reduce bias between two compared groups: propensity score / 中华流行病学杂志

<p><b>OBJECTIVE</b>Through introduction of principal theory and algorithm of propensity score to design SAS macro programs for binary data.</p><p><b>METHODS</b>Propensity score method was used to compare the differences of character variables between two groups, and the association of DNR (Do Not Resuscitate) with the mortality of congestive heart failure was evaluated with different methods.</p><p><b>RESULTS</b>Significant differences among the character variables between two groups were effectively balanced with stratification or matching method. The odds ratios of DNR with the in-hospital mortality rate of congestive heart failure were estimated identical with different algorithms and to find that the association of DNR to in-hospital mortality was highly significant.</p><p><b>CONCLUSION</b>Propensity score was a good algorithm that could be used to analyze any kind of observational data for matching the effects among the character variables.</p>